D B van Rossum et al.
The Journal of biological chemistry, 275(37), 28562-28568 (2000-07-06)
The mechanism for coupling between Ca(2+) stores and store-operated channels (SOCs) is an important but unresolved question. SOC-mediated Ca(2+) entry is complex and may reflect more than one type of channel and coupling mechanism. To assess such possible divergence the...
Wenbin Zhong et al.
Nature communications, 7, 12702-12702 (2016-09-02)
Metabolic pathways are reprogrammed in cancer to support cell survival. Here, we report that T-cell acute lymphoblastic leukemia (T-ALL) cells are characterized by increased oxidative phosphorylation and robust ATP production. We demonstrate that ORP4L is expressed in T-ALL but not...
Shaily Malik et al.
Frontiers in molecular neuroscience, 10, 404-404 (2017-12-21)
Human immunodeficiency virus-1 (HIV-1) infection compromises the central nervous system (CNS) in a significant number of infected individuals, resulting in neurological dysfunction that ranges from minor cognitive deficits to frank dementia. While macrophages/microglia are the predominant CNS cells infected by...
Dandan Wu et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 94, 514-522 (2017-08-07)
Cisplatin (DDP) is the most commonly used drug in testicular cancer. However, drug resistance severely limits its clinical use and the underlying mechanisms need to be further clarified. The aim of present study was to investigate the role of ATP/IP
Yong-Bo Li et al.
Cell calcium, 68, 24-33 (2017-11-14)
Animal steroid hormones stimulate extracellular Ca