55785

Sigma-Aldrich

Atto Oxa12 NHS ester

NACRES:
NA.32
Pricing and availability is not currently available.

fluorescence

λex 663 nm; λem 684 nm

Quality Level

storage temp.

−20°C

General description

ATTO Oxa12 NHS ester is a red-emitting dye and a lipophilic variety of ATTO 655. Characteristic features of the label are strong absorption, good fluorescence quantum yield, very little triplet formation, excellent thermal and photo-stability, and outstanding ozone resistance. ATTO Oxa12 NHS ester is a cationic dye (charge +1). Absorption and fluorescence are pH independent in the range pH 2 to 11, used in typical applications. ATTO Oxa12 NHS ester shows excellent solubility in organic solvents like DMF, DMSO or acetonitrile.

Application

Atto Oxa12 NHS ester is used to label molecules via conjugation to primary amine groups. The dye is designed for application in the area of life science, e.g. labeling of DNA, RNA or proteins.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

RIDADR

NONH for all modes of transport

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Antibody transfection into neurons as a tool to study disease pathogenesis.
Douglas JN, Gardner LA, et al.
Journal of Visualized Experiments, 26, 4154-4154 (2012)
Yaodong Chen et al.
Biochemistry, 50(21), 4675-4684 (2011-04-23)
E. coli FtsZ has no native tryptophan. We showed previously that the mutant FtsZ L68W gave a 2.5-fold increase in trp fluorescence when assembly was induced by GTP. L68 is probably buried in the protofilament interface upon assembly, causing the...
Jennifer Z Yao et al.
Journal of the American Chemical Society, 134(8), 3720-3728 (2012-01-14)
Methods for targeting of small molecules to cellular proteins can allow imaging with fluorophores that are smaller, brighter, and more photostable than fluorescent proteins. Previously, we reported targeting of the blue fluorophore coumarin to cellular proteins fused to a 13-amino...
Kiyohiko Kawai et al.
Journal of the American Chemical Society, 133(39), 15568-15577 (2011-08-31)
Photoinduced charge-transfer fluorescence quenching of a fluorescent dye produces the nonemissive charge-separated state, and subsequent charge recombination makes the reaction reversible. While the information available from the photoinduced charge-transfer process provides the basis for monitoring the microenvironment around the fluorescent...

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