56963

Sigma-Aldrich

Atto Thio12

PubChem Substance ID:
NACRES:
NA.32
Pricing and availability is not currently available.

Quality Level

fluorescence

λex 579 nm; λem 609 nm

storage temp.

−20°C

SMILES string

O-Cl(=O)(=O)=O.CN(C)c1ccc2c(SC3=C\C(C=CC3=C2c4ccccc4C(=O)N(C)CCCC(O)=O)=N+(\C)C)c1

InChI

1S/C29H31N3O3S.ClHO4/c1-30(2)19-12-14-23-25(17-19)36-26-18-20(31(3)4)13-15-24(26)28(23)21-9-6-7-10-22(21)29(35)32(5)16-8-11-27(33)34;2-1(3,4)5/h6-7,9-10,12-15,17-18H,8,11,16H2,1-5H3;(H,2,3,4,5)

InChI key

CNHBWUJLSIHMSI-UHFFFAOYSA-N

Application

Atto Thio12 is a new label closely related to the well-known rhodamines for coupling to biomolecules such as DNA, RNA or proteins. The characteristic feature of the label is high yield of triplet formation. The dye is moderately hydrophilic.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

RIDADR

NONH for all modes of transport

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Andriy Chmyrov et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 7(11), 1378-1385 (2008-10-30)
Photo-induced switching of dyes into dark, long-lived states, such as a triplet state, has recently gained increasing interest, as a means to achieve ultra-high optical resolution. Additionally, these long lived states are often highly environment-sensitive and their photodynamics can thus...
Marcia Levitus et al.
Quarterly reviews of biophysics, 44(1), 123-151 (2010-11-27)
The breakthroughs in single molecule spectroscopy of the last decade and the recent advances in super resolution microscopy have boosted the popularity of cyanine dyes in biophysical research. These applications have motivated the investigation of the reactions and relaxation processes...

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