68152

Sigma-Aldrich

Atto 580 Q maleimide

≥90% (coupling to thiols)

MDL number:
NACRES:
NA.32
Pricing and availability is not currently available.

Quality Level

assay

≥90% (coupling to thiols)

application(s)

UV/Vis spectroscopy: suitable

suitability

corresponds for UV test

storage temp.

−20°C

Application

Atto 580Q is a new quencher for fluorescence characterized by high molecular absorption (110.000). Atto 580Q is characterized by a high photostability and thermostability. It is moderately hydrophilic, and soluble in polar solvents as DMF or DMSO. Maleimides are well suited for coupling to thiol groups. This is similar to iodacetamides, but maleimides do react more thiol selective. They do not show significant reaction with histidine or methionine. Hydrolysis of maleimides to a mixture of isomeric nonreactive maleamic acids can compete significantly with thiol modification, particularly above pH 8. Maleimides may be used for labeling of amines, which usually requires a higher pH than reaction of maleimides with thiols.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin

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