All Photos(1)
Synonym(s):
3-Mercapto-1,2,4-triazole
Empirical Formula (Hill Notation):
C2H3N3S
CAS Number:
Molecular Weight:
101.13
Beilstein/REAXYS Number:
107731
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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assay
97%
mp
221-224 °C (lit.)
solubility
H2O: soluble 50 g/L
SMILES string
Sc1nc[nH]n1
InChI
1S/C2H3N3S/c6-2-3-1-4-5-2/h1H,(H2,3,4,5,6)
InChI key
AFBBKYQYNPNMAT-UHFFFAOYSA-N
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General description
1H-1,2,4-Triazole-3-thiol is a mercapto-substituted 1,2,4-triazole ligand and exhibits tautomerism in solution. 1H-1,2,4-Triazole-3-thiol forms novel luminescent polymers with cadmium(II) salts. 1H-1,2,4-Triazole-3-thiol undergoes regioselective S-alkylation to form a series of S-substituted derivatives.
Application
1H-1,2,4-Triazole-3-thiol was used in a study to design a surface enhanced Raman scattering based probe for fast and accurate detection of DNA markers.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Lan Sun et al.
Analytical chemistry, 79(11), 3981-3988 (2007-05-01)
To provide rapid and accurate detection of DNA markers in a straightforward, inexpensive, and multiplex format, an alternative surface-enhanced Raman scattering based probe was designed and fabricated to covalently attach both DNA probing sequence and nonfluorescent Raman tags to the
Anion-induced coordination versatility of 1H-1, 2, 4-triazole-3-thiol (HtrzSH) affording a new hybrid system of cadmium (II) polymers: synthesis, structure, and luminescent properties.
Zhang RB, et al.
Crystal Growth & Design, 8(7), 2562-2573 (2008)
A histochemical study of muscles of mice infected with Trichinella spiralis.
H N Awadalla et al.
Journal of the Egyptian Society of Parasitology, 12(1), 33-39 (1982-06-01)
Synthesis of novel 1, 3-substituted 1H-[1, 2, 4]-triazole-3-thiol derivatives.
Eliazyan KA, et al.
Heteroatom Chem., 20(7), 405-410 (2009)
Effect of some new antibilharzial drugs on oxygen consumption of mouse diaphragm and liver homogenates in experimental bilharziasis.
S M Amin et al.
Journal of the Egyptian Society of Parasitology, 12(1), 107-114 (1982-06-01)
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