MilliporeSigma
All Photos(3)

106615

Sigma-Aldrich

2,2-Bis(hydroxymethyl)propionic acid

98%

Synonym(s):
Bis-MPA, DMPA®, Dimethylolpropionic acid
Linear Formula:
(HOCH2)2C(CH3)COOH
CAS Number:
Molecular Weight:
134.13
Beilstein:
1756385
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

vapor density

<1 (vs air)

Quality Level

assay

98%

form

solid

mp

189-191 °C (lit.)

solubility

H2O: soluble
acetone: slightly soluble
benzene: insoluble
methanol: soluble

SMILES string

CC(CO)(CO)C(O)=O

InChI

1S/C5H10O4/c1-5(2-6,3-7)4(8)9/h6-7H,2-3H2,1H3,(H,8,9)

InChI key

PTBDIHRZYDMNKB-UHFFFAOYSA-N

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Application

2,2-Bis(hydroxymethyl)propionic acid based fourth generation tridendron dendrimer having 48 hydroxyl groups was synthesized[1].
2,2-Bis(hydroxymethyl)propionic acid is commonly used as an AB2 monomer for the synthesis of hyperbranched (hb) polymers and dendrimers.[2][3]
2,2-Bis(hydroxymethyl)propionic acid was used in the synthesis and characterization studies of polyurethane dispersion modified with polymethylsiloxane (Si-PUD) and its nanocomposites incorporated with clays[4].2,2-Bis(hydroxymethyl)propionic acid based dendrimers have potent applications as delivery systems for potent anticancer drugs such as cisplatin and doxorubicin, as well as agents for both boron neutron capture therapy and photodynamic therapy[5].
Simple derivatives of this acid have been used to construct dendritic architectures via the "click" azide-acetylene cycloaddition.[6]

Packaging

100, 500 g in poly bottle
3, 12 kg in poly drum

Legal Information

DMPA is a registered trademark of GEO Specialty Chemicals, Inc.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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