108340

3-Hydroxy-2-quinoxalinecarboxylic acid

97%

• Empirical Formula (Hill Notation): C₉H₆N₂O₃
• CAS Number: 1204-75-7
• Molecular Weight: 190.16
• EC Number: 214-877-4
• MDL number: MFCD00006726
• UNSPSC Code: 12352100
• PubChem Substance ID: 24846662
• NACRES: NA.22

Properties

• assay: 97%
• mp: 267-268 °C (lit.)
• functional group: carboxylic acid
• SMILES string: OC(=O)c1nc2ccccc2nc1O
• InChI: 1S/C9H6N2O3/c12-8-7(9(13)14)10-5-3-1-2-4-6(5)11-8/h1-4H,(H,11,12)(H,13,14)
• InChI key: NMOWGWOAPRKWIR-UHFFFAOYSA-N

Description

Application

3-Hydroxy-2-quinoxalinecarboxylic acid was used to study the sorption of ionizable organic compounds to an estuarine sediment[1]. It was used in the preparation of Zinc(II)-quinoxaline complexes which was characterized by X-ray crystallography and fluorescence spectroscopy[2].

Biochem/physiol Actions

3-Hydroxy-2-quinoxalinecarboxylic acid is an antagonist of excitatory amino acids and possesses anticonvulsant properties[3]. It inhibits the ²²Na⁺ efflux produced in ²²Na⁺-preloaded brain slices by N-methyl-D-aspartate and kainate[4].

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves