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MilliporeSigma

109258

Methyl propionate

99%

Synonym(s):

Methyl propanoate, Propionic acid methyl ester

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$39.50

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$103.00

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About This Item

Linear Formula:
CH3CH2COOCH3
CAS Number:
Molecular Weight:
88.11
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
39022202
UNSPSC Code:
12352100
EC Number:
209-060-4
MDL number:
Beilstein/REAXYS Number:
1737628

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Product Name

Methyl propionate, 99%

InChI key

RJUFJBKOKNCXHH-UHFFFAOYSA-N

InChI

1S/C4H8O2/c1-3-4(5)6-2/h3H2,1-2H3

SMILES string

CCC(=O)OC

vapor density

3 (vs air)

vapor pressure

40 mmHg ( 11 °C)
85.3 mmHg ( 25 °C)

assay

99%

autoignition temp.

876 °F

expl. lim.

13 %

refractive index

n20/D 1.376 (lit.)

bp

79 °C (lit.)

mp

−88 °C (lit.)

solubility

H2O: soluble 16 parts
alcohol: miscible
diethyl ether: miscible

density

0.915 g/mL at 25 °C (lit.)

functional group

ester

Quality Level

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1 of 4

This Item
W27420881988W245615
assay

99%

assay

≥98%

assay

≥99.8% (GC)

assay

≥97%

Quality Level

100

Quality Level

400

Quality Level

100

Quality Level

400

solubility

H2O: soluble 16 parts, diethyl ether: miscible, alcohol: miscible

solubility

-

solubility

-

solubility

-

density

0.915 g/mL at 25 °C (lit.)

density

0.915 g/mL at 25 °C (lit.)

density

0.915 g/mL at 25 °C (lit.)

density

0.888 g/mL at 25 °C (lit.)

bp

79 °C (lit.)

bp

79 °C (lit.)

bp

79 °C (lit.)

bp

99 °C (lit.)

refractive index

n20/D 1.376 (lit.)

refractive index

n20/D 1.376 (lit.)

refractive index

n20/D 1.376 (lit.)

refractive index

n20/D 1.384 (lit.)

General description

Methyl propionate is an efficient solvent for Porcine Pancreatic Lipase (PPL)-catalyzed transesterification reaction of various diols[1]. It is commonly used in organic synthesis. It undergoes vapour-phase aldol condensation with formaldehyde to form methyl methacrylate[2].
Karl Fischer′s pyridine-free single solution is a reagent used for volumetric Karl Fischer titration, designed to determine the water content in various samples. This solution is free of pyridine, making it a safer and more environmentally friendly option compared to traditional Karl Fischer reagents. It ensures rapid titration with consistent and stable results, making it ideal for precise water analysis.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

28.4 °F - closed cup

flash_point_c

-2 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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PPL-catalyzed resolution of 1, 2-and 1, 3-diols in methyl propionate as solvent. An application of the tandem use of enzymes.
Janssen AJM and Zwanenburg B.
Tetrahedron, 47(35), 7409-7416 (1991)
Formation of methyl methacrylate by condensation of methyl propionate with formaldehyde over silica-supported cesium hydroxide catalysts.
Ai M.
Applied Catalysis A: General, 288(1), 211-215 (2005)
Sang-Ryong Lee et al.
The Science of the total environment, 610-611, 992-996 (2017-08-26)
This report proposes a new approach to evaluate the odour nuisance of cattle manure samples from three different cattle breeds (i.e., native cattle, beef cattle, and milk cow) by means of quantification and speciation of volatile fatty acids (VFAs). To
Jonathan Slaughter et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 23(1), 167-175 (2016-10-30)
In investigating and seeking to mimic the reactivity of trimethylaluminium (TMA) with synthetic, ester-based lubricating oils, the reaction of methyl propionate 1 was explored with 1, 2 and 3 equivalents of the organoaluminium reagent. Spectroscopic analysis points to the formation of
Ileana M Pazos et al.
Angewandte Chemie (International ed. in English), 53(24), 6080-6084 (2014-05-03)
The ability to quantify the local electrostatic environment of proteins and protein/peptide assemblies is key to gaining a microscopic understanding of many biological interactions and processes. Herein, we show that the ester carbonyl stretching vibration of two non-natural amino acids

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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