112291

Sigma-Aldrich

Ethyl salicylate

99%

Synonym(s):
Ethyl 2-hydroxybenzoate
Linear Formula:
2-(HO)C6H4CO2C2H5
CAS Number:
Molecular Weight:
166.17
Beilstein/REAXYS Number:
907659
EC Number:
MDL number:
eCl@ss:
39024568
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

vapor pressure

0.05 mmHg ( 25 °C)

assay

99%

refractive index

n20/D 1.522 (lit.)

bp

234 °C (lit.)

mp

1 °C (lit.)

density

1.131 g/mL at 25 °C (lit.)

SMILES string

CCOC(=O)c1ccccc1O

InChI

1S/C9H10O3/c1-2-12-9(11)7-5-3-4-6-8(7)10/h3-6,10H,2H2,1H3

InChI key

GYCKQBWUSACYIF-UHFFFAOYSA-N

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General description

Ethyl salicylate was hydrolysed to salicylic acid by the use of an extractive electrospray ionisation (EESI) device.

Application

Ethyl salicylate is a non-steroidal analgesic, anti-inflammatory and antirrheumatic drug. Its complexation with β-cyclodextrin was studied using reversed-phase liquid chromatography.

Packaging

100, 250 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xn

Risk Statement

22-36/38-52/53

Safety Statement

26-36

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

212.0 °F

Flash Point(C)

100 °C

C Chen et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(2), 755-763 (2009-12-26)
Nicotine and flavorant compound levels were measured in 10 "mint"-related sub-brands and 8 "wintergreen" sub-brands of smokeless tobacco (SLT). Also analyzed were "mint"-related and "wintergreen" confectionery products. Of the "mint" SLT, "Timberwolf Packs Mint Pouches" contained the highest menthol level...
Xiao-lan Chen et al.
Guang pu xue yu guang pu fen xi = Guang pu, 24(3), 379-380 (2005-03-12)
Atherton-Todd reaction has been extensively applied to the synthesis of phosphates and phosphoroamidates. Under Atherton-Todd reaction conditions, dialkyl phosphites were probably transformed into diakyl phosphorochloridates. We have tried to use Atherton-Todd reaction to synthesize phosphate of salicylic-acid. But when the...
A J Collins et al.
Annals of the rheumatic diseases, 43(3), 411-415 (1984-06-01)
A topically applied rubifacient delivered by aerosol (Deep-Heat) was studied. After spray application to the forearms of volunteers, without massage, the erythema produced was measured by thermography and correlated with the concentration of 2 salicylate components of the mixture found...
T Kakkar et al.
Journal of chromatography. B, Biomedical sciences and applications, 718(1), 69-75 (1998-12-01)
A gas chromatographic-mass spectrometric (GC-MS) assay was developed for the quantitative analysis of methyl salicylate (MeS), ethyl salicylate (ES) and salicylic acid (SA) from biological fluids. The method was validated from 100-microl rat liver homogenate preparations (5 mg/ml protein) in...
Amnon C Sintov et al.
Journal of controlled release : official journal of the Controlled Release Society, 79(1-3), 113-122 (2002-02-21)
The aim of this study was to investigate the percutaneous penetration and dermal metabolism of a new potential anti-acne prodrug--TU-2100 [bis(o-carboxyphenyl ethyl ester)nonanedioate] in guinea pigs. The fluxes of this agent through excised skin after applications of TU-2100 gels at...

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