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MilliporeSigma

112747

N-Acetylsulfanilyl chloride

98%

Synonym(s):

4-Acetamidobenzenesulfonyl chloride

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100 G

$79.40

1 KG

$225.00

$79.40


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About This Item

Linear Formula:
4-(CH3CONH)C6H4SO2Cl
CAS Number:
Molecular Weight:
233.67
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-485-1
Beilstein/REAXYS Number:
746676
MDL number:
Assay:
98%

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InChI key

GRDXCFKBQWDAJH-UHFFFAOYSA-N

InChI

1S/C8H8ClNO3S/c1-6(11)10-7-2-4-8(5-3-7)14(9,12)13/h2-5H,1H3,(H,10,11)

SMILES string

CC(=O)Nc1ccc(cc1)S(Cl)(=O)=O

assay

98%

mp

142-145 °C (dec.) (lit.)

functional group

amide

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This Item
306657147249119946
assay

98%

assay

98%

assay

99%

assay

98%

mp

142-145 °C (dec.) (lit.)

mp

-

mp

-

mp

10-12 °C (lit.)

functional group

amide

functional group

-

functional group

acyl chloride

functional group

acyl chloride, fluoro

General description

L-hydroxyproline has been derivatized with N-acetylsulfanilyl chloride and 5-chlorovaleric acid during the synthesis of the haptens HP1 and HP2[1].

Application

N-Acetylsulfanilyl chloride is used in the synthesis of N1,N1-dimethylsulfanilamide as the internal standard in the reaction. The reaction is used to determine tramadol and its O-desmethylated metabolite in blood plasma[2].

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Li L Wang et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 48(1), 9-15 (2012-10-04)
China's government has prohibited the addition of simply hydrolyzed animal protein from solid leather waste into milk. The objective of this study was to produce a monoclonal antibody against L-hydroxyproline, a special amino acid in hydrolyzed animal protein. L-hydroxyproline was
Ning Li et al.
European journal of medicinal chemistry, 155, 531-544 (2018-06-18)
Ten novel symmetric 3,5-bis(arylidene)-4-piperidone derivatives (BAPs, 1-10) and fourteen dissymmetric BAPs (11-24) were synthesized and evaluated the cytotoxicity. All of the compounds have been screened for their anti-inflammatory activity characterized by evaluating their inhibitory effects on LPS-induced IL-6, TNF-α secretion.

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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