112771

Sigma-Aldrich

Methyl isothiocyanate

97%

Linear Formula:
CH3NCS
CAS Number:
Molecular Weight:
73.12
Beilstein/REAXYS Number:
605319
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

vapor pressure

21 mmHg ( 20 °C)

assay

97%

bp

117-118 °C (lit.)

mp

30-34 °C (lit.)

solubility

H2O: slightly soluble

density

1.069 g/cm3 at 25 °C (lit.)

SMILES string

CN=C=S

InChI

1S/C2H3NS/c1-3-2-4/h1H3

InChI key

LGDSHSYDSCRFAB-UHFFFAOYSA-N

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General description

Methyl isothiocyanate (MITC) is a common soil fumigant byproduct that is toxic and corrosive, skin and respiratory irritant. It can be degraded and removed from contaminated waters by free radical reactions†.

Application

Methyl isothiocyanate can be used:
  • For amino acid sequence analysis
  • To study the effect of pesticide Metam (methyl isothiocyanate is its active ingredient) in the streamside microbial communities

Packaging

100, 500 g in Sure/Seal™
5 g in glass bottle

Signal Word

Danger

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 2477 3(6.1) / PGI

WGK Germany

WGK 3

Flash Point(F)

86.0 °F - closed cup

Flash Point(C)

30 °C - closed cup

Microbial ecology, toxicology and chemical fate of methyl isothiocyanate in riparian soils from the upper Sacramento river.
Environmental Toxicology and Chemistry / Setac, 15(10), 1694-1701 (1996)
Keiji Nishiwaki et al.
Bioorganic & medicinal chemistry, 15(3), 1341-1345 (2006-11-28)
Tetrahydrobenzotriazines, a novel class of heterocyclic compounds, were synthesized. Examination of their biological activities resulted in the discovery that some of them possess potent nematocidal activity.
YongLin Ren et al.
Pest management science, 68(2), 194-201 (2011-07-23)
Methyl bromide is being phased out for use on stored commodities, as it is listed as an ozone-depleting substance, and phosphine is the fumigant widely used on grains. However, phosphine resistance occurs worldwide, and phosphine fumigation requires a long exposure...
William S Cain et al.
Regulatory toxicology and pharmacology : RTP, 58(2), 173-180 (2010-07-17)
An unpublished laboratory study by Russell and Rush (1996) showed that human subjects sense the presence of methyl isothiocyanate (MITC) via the eyes at concentrations as low as hundreds of ppb in air, with dependence upon duration of exposure. The...
Katy L Swancutt et al.
Chemosphere, 81(3), 339-344 (2010-08-11)
Methyl isothiocyanate (MITC), a toxic and corrosive skin and respiratory irritant, is a common soil fumigant byproduct which has become an atmospheric, aqueous, and soil contaminant. The work described here examines the degradation and potential removal of MITC from contaminated...

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