114081

4-(Benzyloxy)benzyl chloride

97%

• Synonym(s): 4-Chloromethyl-α-phenylanisole
• Linear Formula: C₆H₅CH₂OC₆H₄CH₂Cl
• CAS Number: 836-42-0
• Molecular Weight: 232.71
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24847156
• EC Number: 212-648-3
• Beilstein/REAXYS Number: 882526
• MDL number: MFCD00000916
• Assay: 97%
• Form: solid

Properties

• Quality Segment: 200
• assay: 97%
• form: solid
• mp: 77-79 °C (lit.)
• functional group: chloro, phenyl
• storage temp.: 2-8°C
• SMILES string: ClCc1ccc(OCc2ccccc2)cc1
• InChI: 1S/C14H13ClO/c15-10-12-6-8-14(9-7-12)16-11-13-4-2-1-3-5-13/h1-9H,10-11H2
• InChI key: UYQPSKUPEXAQRJ-UHFFFAOYSA-N

Description

General description

4-(Benzyloxy)benzyl chloride acts as a solid support to readily determine the loading of the corresponding polymer-bound acids by direct cleavage. This was determined while studying the coupling of substituted aromatic, heterocyclic, and alkyl carboxylates to the resin.

Application

4-(benzyloxy)benzyl chloride is used in the preparation of 4-aryl-3,4-dihydropyrimidine-5-carboxylates (DHPMs) which exhibits a wide spectrum of biological effects.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Codes: H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges