Skip to Content
MilliporeSigma

Skip To

115533

CDI

greener alternative

≥90.0% (proton, NMR), for peptide synthesis

Synonym(s):

1,1′-Carbonyldiimidazole

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice
5 g

Available to ship TODAYfromMILWAUKEE

$39.90
10 g

Available to ship TODAYfromMILWAUKEE

$67.40
$57.29
25 g

Available to ship TODAYfromMILWAUKEE

$125.00
100 g

Estimated to ship onJuly 09, 2026fromMILWAUKEE

$326.00
500 g

Available to ship TODAYfromMILWAUKEE

$900.00
1 kg

Estimated to ship onJuly 09, 2026fromMILWAUKEE

$953.00
25 kg

Estimated to ship onJune 05, 2026fromMILWAUKEE

Inquire

About This Item

Empirical Formula (Hill Notation):
C7H6N4O
CAS Number:
Molecular Weight:
162.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352115
EC Number:
208-488-9
MDL number:
Beilstein/REAXYS Number:
6826

$39.90


Available to ship TODAYDetails


Request a Bulk Order
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


Product Name

CDI, reagent grade

grade

reagent grade

Quality Level

assay

≥90.0% (proton, NMR)

form

solid

reaction suitability

reaction type: Carbonylations

greener alternative product characteristics

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

117-122 °C (lit.)

application(s)

peptide synthesis

greener alternative category

SMILES string

O=C(n1ccnc1)n2ccnc2

InChI

1S/C7H6N4O/c12-7(10-3-1-8-5-10)11-4-2-9-6-11/h1-6H

InChI key

PFKFTWBEEFSNDU-UHFFFAOYSA-N

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. 1,1′-carbonyldiimidazole (CDI) is an alternative to highly toxic insidious poison phosgene and thus aligns with the principle "Designing Safer Chemicals". For more information see the article Controlled Synthesis of Asymmetric Dialkyl and Cyclic Carbonates Using the Highly Selective Reactions of Imidazole Carboxylic Esters.

Application

Coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides.[1] Also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
8.5105421860265365
form

solid

form

powder

form

solid

form

powder

grade

reagent grade

grade

-

grade

-

grade

-

assay

≥90.0% (proton, NMR)

assay

≥97.0% (GC)

assay

≥97.0% (T)

assay

99.5% trace metals basis

mp

117-122 °C (lit.)

mp

116-120 °C

mp

115-122 °C, 117-122 °C (lit.)

mp

320.9 °C (lit.)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

greener alternative product characteristics

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

greener alternative product characteristics

-


Still not finding the right product?

Explore all of our products under CDI


signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library


Articles

N-Acylimidazoles and carbonylimidazoles are reactive intermediates used for amino compound acylation, surpassing DCC as coupling reagents.


Polym. Mater. Sci. Eng., 61, 936-936 (1989)
Inorganic Chemistry, 32, 3052-3052 (1993)
The Journal of Organic Chemistry, 54, 5620-5620 (1989)



Global Trade Item Number

SKUGTIN
115533-1KG04061826731888
115533-10G04061838703330
115533-500G04061838703354
115533-25G04061838703347
115533-5G04061838703361
115533-100G04061838703323
115533-25KG04061833431450

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

Reviews

No rating value