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MilliporeSigma

122505

2,3-Dihydroxypyridine

95%

Synonym(s):

2,3-Pyridinediol

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$633.00

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About This Item

Empirical Formula (Hill Notation):
C5H5NO2
CAS Number:
16867-04-2
Molecular Weight:
111.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24847492
EC Number:
240-887-3
Beilstein/REAXYS Number:
109848
MDL number:
MFCD00006271
Assay:
95%

Key Documents

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InChI key

GGOZGYRTNQBSSA-UHFFFAOYSA-N

InChI

1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)

SMILES string

Oc1cccnc1O

assay

95%

mp

245 °C (dec.) (lit.)

Quality Level

100

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1 of 4

This Item
D120405D120006A50401
2,3-Dihydroxypyridine 95%

Sigma-Aldrich

122505

2,3-Dihydroxypyridine

4,6-Dihydroxypyrimidine 98%

Sigma-Aldrich

D120405

4,6-Dihydroxypyrimidine

2,6-Dihydroxypyridine hydrochloride 97%

Sigma-Aldrich

D120006

2,6-Dihydroxypyridine hydrochloride

2-Amino-4,6-dihydroxypyrimidine 98%

Sigma-Aldrich

A50401

2-Amino-4,6-dihydroxypyrimidine

assay

95%

assay

98%

assay

97%

assay

98%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mp

245 °C (dec.) (lit.)

mp

>300 °C (lit.)

mp

206-208 °C (dec.) (lit.)

mp

>300 °C (lit.)

Application

2,3-Dihydroxypyridine(DHP) was used in the synthesis of DHP loaded amberlite XAD-2 via azo coupler[1]. It was used in the synthesis of new macromolecular chelators by loading DHP on cellulose via linkers -NH-CH2-CH2-NH-SO2-C6H4-N=N- and -SO2-C6H4-N=N[2].

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
STBK2335
STBJ9108
STBJ6462
STBJ0129
STBG7923

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Jayakanth Kankanala et al.
European journal of medicinal chemistry, 141, 149-161 (2017-10-17)
Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) is the only HIV enzymatic function not targeted by current antiviral drugs. Although various chemotypes have been reported to inhibit HIV RNase H, few have shown significant antiviral
Lei Wang et al.
European journal of medicinal chemistry, 156, 680-691 (2018-07-23)
Human immunodeficiency virus (HIV) reverse transcriptase (RT)-associated ribonuclease H (RNase H) remains an unvalidated drug target. Reported HIV RNase H inhibitors generally lack significant antiviral activity. We report herein the design, synthesis, biochemical and antiviral evaluations of a new 6-biphenylmethyl
Lei Wang et al.
European journal of medicinal chemistry, 156, 652-665 (2018-07-23)
Human immunodeficiency virus (HIV) reverse transcriptase (RT) associated ribonuclease H (RNase H) remains the only virally encoded enzymatic function not targeted by current drugs. Although a few chemotypes have been reported to inhibit HIV RNase H in biochemical assays, their
T Sahlu et al.
Journal of animal science, 73(1), 172-176 (1995-01-01)
Sixteen growing Alpine wethers (average BW 35 +/- 2 kg) were assigned to one of four treatments to evaluate tissue retention of the leucaena toxins mimosine (MIM) and 2,3-dihydroxypyridine (2,3-DHP). Treatments were infused i.v. for 2 d and were 1)
M J Raxworthy et al.
Biochemical pharmacology, 32(8), 1361-1364 (1983-04-15)
Despite its structural similarity to catechol, 2,3-dihydroxypyridine is not a substrate but a "dead-end" inhibitor of purified pig liver catechol-O-methyltransferase. It inhibits the methylation of 3,4-dihydroxyphenylacetic acid competitively with an inhibitor constant of 15 microM. Against the methyl donor, S-adenosyl-L-methionine
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