124036

Sigma-Aldrich

1-Bromo-3-chlorobenzene

99%

Linear Formula:
BrC6H4Cl
CAS Number:
Molecular Weight:
191.45
Beilstein/REAXYS Number:
1446353
EC Number:
MDL number:
eCl@ss:
39080308
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99%

refractive index

n20/D 1.576 (lit.)

bp

196 °C (lit.)

density

1.63 g/mL at 25 °C (lit.)

SMILES string

Clc1cccc(Br)c1

InChI

1S/C6H4BrCl/c7-5-2-1-3-6(8)4-5/h1-4H

InChI key

JRGGUPZKKTVKOV-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

1-Bromo-3-chlorobenzene undergoes bromine-magnesium exchange reactions with i-PrMgCl-LiCl in THF at 0°C and is strongly accelerated by electron-withdrawing substituents. It acts as test substrate to study the application of a new catalytic system for cyanation of various aryl halides using K4[Fe(CN)6] as cyanating source.

Packaging

25, 100 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

176.0 °F - closed cup

Flash Point(C)

80 °C - closed cup

Lei Shi et al.
The Journal of organic chemistry, 74(7), 2760-2764 (2009-03-14)
Competition experiments have been performed to determine the relative reactivities of substituted bromobenzenes, bromonaphthalenes, and 9-bromoanthracene toward i-PrMgCl x LiCl in THF at 0 degrees C. The rates of the bromine-magnesium exchange reactions are accelerated by electron-acceptor substituents, the activating...
Silvina C Pérez et al.
Solid state nuclear magnetic resonance, 87, 18-23 (2017-07-01)
A simple model to explain the NQR lineshape in solids with orientational disorder or substitutional disorder is presented. The particular case of m-chlorobromobenzene is studied. It is based on the assumption that Bromine atoms, of m-chlorobromobenzene molecules, behave as point...
An efficient palladium catalytic system for microwave assisted cyanation of aryl halides.
Hajipour AR, et al.
Journal of Organometallic Chemistry, 696(4), 819-824 (2011)
Nicholas C Pflug et al.
Environmental science & technology, 53(9), 4813-4822 (2019-03-27)
Anilines have been shown to be especially susceptible to single-electron oxidation by excited triplet-state photosensitizers (3sens*), and thus, are good potential candidates to probe the oxidative properties of triplet-state chromophoric dissolved organic matter (3CDOM*). However, steady-state experiments tend to underestimate...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.