124036

1-Bromo-3-chlorobenzene

99%

• Synonym(s): 1-Chloro-3-bromobenzene, 3-Bromo-1-chlorobenzene, 3-Chloro-1-bromobenzene, 3-Chlorophenyl bromide, m-Bromochlorobenzene
• Linear Formula: BrC₆H₄Cl
• CAS Number: 108-37-2
• Molecular Weight: 191.45
• Beilstein/REAXYS Number: 1446353
• EC Number: 203-575-8
• MDL number: MFCD00000568
• UNSPSC Code: 12352100
• eCl@ss: 39080308
• PubChem Substance ID: 24847592
• NACRES: NA.22

Properties

• assay: 99%
• form: liquid
• refractive index: n20/D 1.576 (lit.)
• bp: 196 °C (lit.)
• density: 1.63 g/mL at 25 °C (lit.)
• functional group: bromo; chloro
• SMILES string: Clc1cccc(Br)c1
• InChI: 1S/C6H4BrCl/c7-5-2-1-3-6(8)4-5/h1-4H
• InChI key: JRGGUPZKKTVKOV-UHFFFAOYSA-N

Description

General description

1-Bromo-3-chlorobenzene undergoes bromine-magnesium exchange reactions with i-PrMgCl-LiCl in THF at 0°C and is strongly accelerated by electron-withdrawing substituents[1]. It acts as test substrate to study the application of a new catalytic system for cyanation of various aryl halides using K₄[Fe(CN)₆] as cyanating source[2].

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 176.0 °F - closed cup
• flash_point_c: 80 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter