124214

Sigma-Aldrich

Ethylene glycol butyl ether

99%

Synonym(s):
Butyl glycol, 2-Butoxyethanol
Linear Formula:
CH3(CH2)3OCH2CH2OH
CAS Number:
Molecular Weight:
118.17
Beilstein/REAXYS Number:
1732511
EC Number:
MDL number:
PubChem Substance ID:

vapor density

4.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)
10 mmHg ( 81 °C)

assay

99%

autoignition temp.

473 °F

expl. lim.

10.6 %

availability

not available in USA and Canada

refractive index

n20/D 1.419 (lit.)

bp

169-172.5 °C (lit.)

mp

−75 °C (lit.)

density

0.902 g/mL at 25 °C (lit.)

SMILES string

CCCCOCCO

InChI

1S/C6H14O2/c1-2-3-5-8-6-4-7/h7H,2-6H2,1H3

InChI key

POAOYUHQDCAZBD-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

hazcat

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

storage_class_code

10 - Combustible liquids

WGK Germany

WGK 1

Flash Point(F)

152.6 °F - Pensky-Martens closed cup

Flash Point(C)

67 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Lisa M Kamendulis et al.
Toxicology, 270(2-3), 131-136 (2010-02-16)
2-Butoxyethanol increases hemangiosarcomas selectively in male mouse liver after chronic inhalation through mechanisms that have not fully been elucidated. Hemolysis, a primary toxic effect associated with 2-butoxyethanol exposure in rodents, increased hemosiderin (iron) deposition in Kupffer cells in the liver....
Tawny Hung et al.
Clinical toxicology (Philadelphia, Pa.), 48(6), 569-571 (2010-06-22)
2-butoxyethanol (2BE) is a solvent commonly incorporated into household and industrial cleaning products. Its ingestion causes rapid central nervous system depression, hypotension, and metabolic acidosis attributable to metabolism of the parent compound to butoxyacetic acid (BAA) by alcohol dehydrogenase. Lactic...
Gintautas Korinth et al.
Toxicology letters, 170(2), 97-103 (2007-04-07)
We determined percutaneous absorption kinetics of 2-butoxyethanol (BE) in volunteers using microdialysis. Four male volunteers were dermally exposed twice to 90% and 50% aqueous solutions (v/v) of BE for 4.5h. To determine percutaneous absorption kinetics the concentration of BE was...
Horst Christoph Broding et al.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 9(8), 618-627 (2011-07-28)
Presently, percutaneous absorption of potentially hazardous chemicals in humans can only be assessed in animal experiments, in vitro, or predicted mathematically. Our aim was to demonstrate the proof-of-principle of a novel quantitative in vivo assay for percutaneous absorption: confocal Raman...
Daphna Laifenfeld et al.
Toxicological sciences : an official journal of the Society of Toxicology, 113(1), 254-266 (2009-10-09)
To understand the molecular mechanisms underlying compound-induced hemangiosarcomas in mice, and therefore, their human relevance, a systems biology approach was undertaken using transcriptomics and Causal Network Modeling from mice treated with 2-butoxyethanol (2-BE). 2-BE is a hemolytic agent that induces...

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