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128635

Sigma-Aldrich

2-Hydroxyethyl methacrylate

contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%

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Synonym(s):
1,2-Ethanediol mono(2-methylpropenoate), Glycol methacrylate, HEMA
Linear Formula:
CH2=C(CH3)COOCH2CH2OH
CAS Number:
Molecular Weight:
130.14
Beilstein/REAXYS Number:
1071583
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

vapor density

5 (vs air)

Quality Level

vapor pressure

0.01 mmHg ( 25 °C)

assay

97%

form

liquid

contains

≤250 ppm monomethyl ether hydroquinone as inhibitor

refractive index

n20/D 1.453 (lit.)

bp

67 °C/3.5 mmHg (lit.)

density

1.073 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI key

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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This Item
477028M55909415332
2-Hydroxyethyl methacrylate contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%

128635

2-Hydroxyethyl methacrylate

2-Hydroxyethyl methacrylate ≥99%, contains ≤50 ppm monomethyl ether hydroquinone as inhibitor

477028

2-Hydroxyethyl methacrylate

Methyl methacrylate contains ≤30 ppm MEHQ as inhibitor, 99%

M55909

Methyl methacrylate

density

1.073 g/mL at 25 °C (lit.)

density

1.073 g/mL at 25 °C (lit.)

density

0.936 g/mL at 25 °C (lit.)

density

0.993 g/mL at 25 °C (lit.)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

bp

67 °C/3.5 mmHg (lit.)

bp

67 °C/3.5 mmHg (lit.)

bp

100 °C (lit.)

bp

65 °C/12 mmHg (lit.)

form

liquid

form

-

form

-

form

liquid

contains

≤250 ppm monomethyl ether hydroquinone as inhibitor

contains

≤50 ppm monomethyl ether hydroquinone as inhibitor

contains

≤30 ppm MEHQ as inhibitor

contains

-

General description

2-Hydroxyethyl methacrylate (HEMA) was the first monomer to be used to synthesize hydrogels for biomedical applications.The water swelling properties of HEMA are enhanced by copolymerization with more hydrophilic monomers.HEMA finds wide applications for drug delivery.

Application

HEMA is used in the synthesis of biologically functional poly (2-hydroxyethyl methacrylate) (PHEMA) coplymers. It is also used to prepare light responsive membranes of PHEMA, HEMA/ acrylamide based specific drug release hydrogel, and water soluble HEMA/methacrylic acid hydrogel for drug delivery. Effects of HEMA on the migration of dental pulp stem cells (in vitro) may be studied.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

222.8 °F - closed cup

flash_point_c

106 °C - closed cup


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Influence of the ionic character of a drug on its release rate from hydrogels based on 2-hydroxyethylmethacrylate and acrylamide synthesized by photopolymerization
Gomez ML, et al.
Express Polymer Letters, 6(30, 189-197 (2012)
Drake W Williams et al.
Journal of endodontics, 39(9), 1156-1160 (2013-08-21)
Cell migration is an important step in pulpal wound healing. Although components in the resin-based dental materials are known to have adverse effects on pulp wound healing including proliferation and mineralization, their effects on cell migration have been scarcely examined.
Giovanna C R M Schver et al.
International journal of pharmaceutics, 581, 119292-119292 (2020-04-04)
The use of water-insoluble carriers for amorphous solid dispersions (ASDs) has attracted more recent interest as the kinetic solubility profiles (KSP) from these systems can achieve a more sustained level of supersaturation when compared with ASDs based on water-soluble polymers.
Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process.
Scholler K, et al.
Journal of Visualized Experiments, 85, e51680-e51680 (2014)
Thomas J Dursch et al.
Biomaterials, 35(2), 620-629 (2013-10-24)
Two-photon confocal microscopy and back extraction with UV/Vis-absorption spectrophotometry quantify equilibrium partition coefficients, k, for six prototypical drugs in five soft-contact-lens-material hydrogels over a range of water contents from 40 to 92%. Partition coefficients were obtained for acetazolamide, caffeine, hydrocortisone

Articles

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