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128775

4-Hydroxypiperidine

98%

Synonym(s):

4-Piperidinol

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5 g

Available to ship TODAYfromMILWAUKEE

$40.80
25 g

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$113.00
100 g

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$215.00

About This Item

Empirical Formula (Hill Notation):
C5H11NO
CAS Number:
Molecular Weight:
101.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
226-373-1
Beilstein/REAXYS Number:
102738
MDL number:
Assay:
98%

$40.80


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Quality Level

assay

98%

bp

108-114 °C/10 mmHg (lit.)

functional group

hydroxyl

SMILES string

OC1CCNCC1

InChI

1S/C5H11NO/c7-5-1-3-6-4-2-5/h5-7H,1-4H2

InChI key

HDOWRFHMPULYOA-UHFFFAOYSA-N

General description

The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied[1]. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H(3) receptor[2].

Application

4-Hydroxypiperidine (4-Piperidinol) can be used in the synthesis of a highly potent and selective IP (PGI(2) receptor) agonist.[3] It can also be used in the study of copper-catalyzed N- versus O-arylation.[4]

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assay

98%

assay

≥98.0% (NT)

assay

99%

assay

99%

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

bp

108-114 °C/10 mmHg (lit.)

bp

-

bp

-

bp

-

functional group

hydroxyl

functional group

hydroxyl

functional group

-

functional group

-


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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S Sebastian et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 75(3), 941-952 (2010-01-09)
In this work, we report a combined experimental and theoretical study on molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine (4-HP). The FT-IR solid phase (4000-400 cm(-1)), FT-IR gas phase (5000-400 cm(-1)) and FT-Raman spectra (3500-50 cm(-1)) of
James T Anderson et al.
Bioorganic & medicinal chemistry letters, 20(21), 6246-6249 (2010-09-14)
Compounds containing a substituted 4-piperidinol core have been found to be potent antagonists of the human H(3) receptor. The compounds exhibited up to a 60-fold preference for inhibiting the human H(3) receptor over the mouse and showed a low binding
N- versus O-arylation of aminoalcohols: orthogonal selectivity in copper-based catalysts.
Alexandr Shafir et al.
Journal of the American Chemical Society, 129(12), 3490-3491 (2007-03-08)



Global Trade Item Number

SKUGTIN
128775-5G04061833320167
128775-25G04061838725943
128775-100G04061838345707

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    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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