Sulfur trioxide trimethylamine complex

NSC 9838, Trimethylamine sulfur trioxide complex
Linear Formula:
(CH3)3N · SO3
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

reaction suitability

reagent type: oxidant


232 °C (dec.) (lit.)

SMILES string




InChI key


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Reactant for sulfation reactions involving:
  • Synthesis of sulfate-conjugated resveratrol metabolites
  • Chitooligosaccharides used for anti-HIV-1 activity
  • Dodecyl thioglycopyranoside used as a surfactant for enantiomeric separation
  • Glycosaminoglycans which facilitate activation of signaling pathways dependent on sulfation pattern
  • Polysaccharides as heparan sulfate mimetics

Nucleophile for the synthesis of α-tosyloxy ketones


5, 100, 500 g in glass bottle



Signal Word


Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


UN 3261 8 / PGII

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Jure Acimovic et al.
PloS one, 8(7), e68031-e68031 (2013-07-12)
24S- and 27-hydroxycholesterol (24OHC and 27OHC) are potent regulators of different biochemical systems in vitro and are the major circulating oxysterols. A small fraction of these oxysterols has been reported to be sulphated but there are no detailed studies. We...
Juliane Strätz et al.
Macromolecular bioscience, 20(2), e1900403-e1900403 (2019-12-31)
Sulfated cellulose (CS) represents an interesting biopolymer due to bioactivity comparable to heparin. However, use of CS for making surface coatings or hydrogels requires the presence of reactive groups for covalent reactions. Here, an approach is presented to oxidize cellulose...
Shuqian Hu et al.
Carbohydrate polymers, 236, 116052-116052 (2020-03-17)
In this study, a series water soluble sulfate polysaccharides (SPS) with different degrees of substitutions (DS = 0.02∼0.28) were prepared using a linear water-insoluble β-d-(1→3)-glucan. SPS-1, SPS-3 and SPS-7 with substitution degrees of 0.02, 0.06 and 0.25 were used as templates to...
Mikael Pedersen et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(4), 482-488 (2017-01-21)
After administration of steroids to animals the steroids are partially metabolised in the liver and kidney to phase 2 metabolites, i.e., glucuronic acid or sulphate conjugates. During analysis these conjugated metabolites are normally deconjugated enzymatically with aryl sulphatase and glucuronidase...
Jianhong Yang et al.
Biopolymers, 103(10), 539-549 (2015-04-11)
The 6-amino-6-deoxychitosan (NC) and their 2, 6-di-N-sulfonated derivatives were prepared via N-phthaloylation, tosylation, azidation, hydrazinolysis, reduction of azide groups and N-sulfonation, and their structures were systematically characterized by FT-IR, 2D HSQC NMR, XRD, gel permeation chromatography (GPC), and elemental analysis....

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