137448

Sigma-Aldrich

2-Methyl-2-oxazoline

98%

Empirical Formula (Hill Notation):
C4H7NO
CAS Number:
Molecular Weight:
85.10
Beilstein/REAXYS Number:
104227
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

98%

refractive index

n20/D 1.434 (lit.)

bp

109.5-110.5 °C (lit.)

density

1.005 g/mL at 25 °C (lit.)

SMILES string

CC1=NCCO1

InChI

1S/C4H7NO/c1-4-5-2-3-6-4/h2-3H2,1H3

InChI key

GUXJXWKCUUWCLX-UHFFFAOYSA-N

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General description

2-Methyl-2-oxazoline undergoes polymerization with 2-butyl-2-oxazoline to form poly(2-oxazoline) block copolymer. It undergoes cationic ring-opening polymerization with 2-(dec-9-enyl)-2-oxazoline to yield copoly(2-oxazoline)s.

Application

2-Methyl-2-oxazoline was used in cationic polymerization of a series of linear 2-alkyl-2-oxazolines under microwave irradiation.

Packaging

100 g in glass bottle

Pictograms

Flame

Signal Word

Danger

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

F

Risk Statement

11

Safety Statement

23-24/25

RIDADR

UN 1993BF 3 / PGII

WGK Germany

WGK 3

Flash Point(F)

68.0 °F - closed cup

Flash Point(C)

20 °C - closed cup

Ondrej Sedlacek et al.
Journal of controlled release : official journal of the Controlled Release Society, 326, 53-62 (2020-06-23)
Poly(2-oxazoline)s represent an emerging class of polymers with increasing potential in biomedical sciences. To date, most of the work on poly(2-oxazoline)-drug conjugates focused on poly(2-ethyl-2-oxazoline) (PEtOx), a biocompatible water-soluble polymer with biological properties similar to polyethylene glycol. However, the more...
Denial Mahata et al.
Scientific reports, 7, 46412-46412 (2017-04-13)
Lignin, one of the most abundant renewable feedstock, is used to develop a biocompatible hydrogel as anti-infective ointment. A hydrophilic polyoxazoline chain is grafted through ring opening polymerization, possess homogeneous spherical nanoparticles of 10-15 nm. The copolymer was covalently modified with...
Pavel Sťahel et al.
Polymers, 11(12) (2019-12-18)
Polyoxazolines are a new promising class of polymers for biomedical applications. Antibiofouling polyoxazoline coatings can suppress bacterial colonization of medical devices, which can cause infections to patients. However, the creation of oxazoline-based films using conventional methods is difficult. This study...
Ye Han Yan et al.
Journal of biomaterials science. Polymer edition, 31(4), 423-438 (2019-12-04)
In this work, the comb-like poly(2-methyl-2-oxazoline) copolymer, poly(2-aminoethyl methacrylate-random-poly(2-methyl-2-oxazoline) (PMOXA-r-AEMA, PMA) is synthesized, and the CuSO4/H2O2-triggered dopamine/PMA co-deposition process is investigated. Ellipsometry, water contact angle (WCA), and X-ray photoelectron spectroscopy (XPS) are used to characterize the thickness, hydrophilicity, and surface...
Yunjiao Che et al.
Soft matter, 16(29), 6733-6742 (2020-06-27)
We report a novel double cross-linked hydrogel system based on polyacrylamide and poly(2-methyl-2-oxazoline) (PMOXA) network chains, as well as on supramolecular host-guest interactions with on-demand tailored mechanical properties. Well-defined vinyl-bearing PMOXA macromonomers, functionalized with either β-cyclodextrin units (β-CD-PMOXA) or adamantane...

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