137456

Sigma-Aldrich

2-Ethyl-2-oxazoline

≥99%

Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
Molecular Weight:
99.13
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

≥99%

refractive index

n20/D 1.437 (lit.)

bp

128.4 °C (lit.)

mp

−62 °C (lit.)

density

0.982 g/mL at 25 °C (lit.)

SMILES string

CCC1=NCCO1

InChI

1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3

InChI key

NYEZZYQZRQDLEH-UHFFFAOYSA-N

General description

2-Ethyl-2-oxazoline undergoes cationic ring opening graft polymerization using tosylated cellulose nanowhisker as macroinitiator.

Application

2-Ethyl-2-oxazoline (EtOx) was used in synthesis of block copolymers of EtOx and styrene by cationic ring-opening polymerization and atom transfer radical polymerization.

Packaging

100, 500 mL in glass bottle

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xn

Risk Statement

10-20/21/22

Safety Statement

16-26-28-36/37/39

RIDADR

UN 1993C 3 / PGIII

WGK Germany

WGK 1

Flash Point(F)

84.2 °F - closed cup

Flash Point(C)

29 °C - closed cup

Mohsen Salmanpour et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 136, 104941-104941 (2019-05-29)
SN-38 is the active metabolite of irinotecan, an FDA-approved chemotherapeutic agent indicated for colorectal carcinoma, which would not be clinically applicable due to its very poorly soluble and hydrolytic degradation properties. To overcome these limitations, it was proposed to conjugate...
Abbas Dadkhah Tehrani et al.
Carbohydrate polymers, 97(1), 98-104 (2013-06-19)
The cellulose nanocrystals, prepared by acid hydrolysis of cotton linter, consisted of slender rods with an average length of 173 nm and diameter of 80 nm, respectively. The surface of obtained cellulose nanocrystals was chemically modified using tosyl chloride and...
Yuanhang Zhou et al.
Biomaterials science, 8(18), 5029-5046 (2020-08-20)
Combination therapy has been proved to be an effective strategy to inhibit metastasis, however, its efficacy is always compromised by the poor delivery efficiency of drugs. In this study, multi pH-sensitive polymer-drug conjugate mixed micelles were fabricated by the self-assembly...
Synthesis of poly (2-ethyl-2-oxazoline)-b-poly (styrene) copolymers via a dual initiator route combining cationic ring-opening polymerization and atom transfer radical polymerization.
Becer CR, et al.
Macromolecules, 41(14), 5210-5215 (2008)
Blaise L Tardy et al.
Biomacromolecules, 20(3), 1421-1428 (2019-02-23)
Metal-phenolic network (MPN) coatings have generated increasing interest owing to their biologically inspired nature, facile fabrication, and near-universal adherence, especially for biomedical applications. However, a key issue in biomedicine is protein fouling, and the adsorption of proteins on tannic acid-based...

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