137456

Sigma-Aldrich

2-Ethyl-2-oxazoline

≥99%

Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
Molecular Weight:
99.13
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

≥99%

refractive index

n20/D 1.437 (lit.)

bp

128.4 °C (lit.)

mp

−62 °C (lit.)

density

0.982 g/mL at 25 °C (lit.)

SMILES string

CCC1=NCCO1

InChI

1S/C5H9NO/c1-2-5-6-3-4-7-5/h2-4H2,1H3

InChI key

NYEZZYQZRQDLEH-UHFFFAOYSA-N

General description

2-Ethyl-2-oxazoline undergoes cationic ring opening graft polymerization using tosylated cellulose nanowhisker as macroinitiator.

Application

2-Ethyl-2-oxazoline (EtOx) was used in synthesis of block copolymers of EtOx and styrene by cationic ring-opening polymerization and atom transfer radical polymerization.

Packaging

100, 500 mL in glass bottle

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xn

Risk Statement

10-20/21/22

Safety Statement

16-26-28-36/37/39

RIDADR

UN 1993C 3 / PGIII

WGK Germany

WGK 1

Flash Point(F)

84.2 °F - closed cup

Flash Point(C)

29 °C - closed cup

Shabnam Sattari et al.
International journal of biological macromolecules, 156, 1126-1134 (2019-11-22)
Although many techniques have been devoted to promote therapeutic purposes of drug carrier systems, however, there are still many challenges in this area. Here, we designed co-loaded delivery systems, composed of curcumin loaded cyclodextrin-graphene oxide core (Cur@CD-GO) and gallic acid...
Ziqi Wang et al.
Acta biomaterialia, 62, 144-156 (2017-08-27)
To concurrently suppress multidrug resistance (MDR) and metastasis of breast cancer cells, paclitaxel (PTX) and honokiol (HNK) were coencapsulated into pH-sensitive polymeric micelles based on poly(2-ethyl-2-oxazoline)-poly(d,l-lactide) (PEOz-PLA). The physicochemical properties of dual drug-loaded PEOz-PLA micelles were characterized in size, drug...
Yuanhang Zhou et al.
Biomaterials science, 8(18), 5029-5046 (2020-08-20)
Combination therapy has been proved to be an effective strategy to inhibit metastasis, however, its efficacy is always compromised by the poor delivery efficiency of drugs. In this study, multi pH-sensitive polymer-drug conjugate mixed micelles were fabricated by the self-assembly...
Synthesis of poly (2-ethyl-2-oxazoline)-b-poly (styrene) copolymers via a dual initiator route combining cationic ring-opening polymerization and atom transfer radical polymerization.
Becer CR, et al.
Macromolecules, 41(14), 5210-5215 (2008)
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