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contains ≤500 ppm sodium carbonate as stabilizer, technical grade, 90%

Acetol, 1-Hydroxy-2-propanone
Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


technical grade






≤500 ppm sodium carbonate as stabilizer

refractive index

n20/D 1.425 (lit.)


145-146 °C (lit.)


−17 °C (lit.)


water: miscible


1.082 g/mL at 25 °C (lit.)

storage temp.


SMILES string




InChI key


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General description

Hydroxyacetone (Acetol) is important for the manufacture of polyols, acrolein, dyes and skin tanning agents. It undergoes asymmetric reduction to yield (R)-1,2-propanediol in the presence of microbial cell catalyst.


Hydroxyacetone was used to study aerobic oxidation of glycerol and propanediol over metal oxide supported gold nanoparticles in methanol.


5, 100, 500 g in glass bottle



Signal Word


Hazard Statements

Hazard Classifications

Flam. Liq. 3

Storage Class Code

3 - Flammable liquids



Flash Point(F)

132.8 °F - closed cup

Flash Point(C)

56 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

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  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. What are the impurities of this Product 138185, Hydroxyacetone?

    The impurities for Product 138185 are not determined.

  6. Is Product 138185, Hydroxyacetone, a liquid or a solid?

    This product is a liquid measured in grams. The density is 1.082 g/mL at 25 °C

  7. Is Product 138185, Hydroxyacetone, on the Toxic Substances Control Act (TSCA) list?

    Yes, Product No. 138185 is currently on the TSCA inventory list.

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Hongliang Zhu et al.
Bioresource technology, 149, 238-243 (2013-10-12)
Escherichia coli Lin43 is a strain which has some mutations in glycerol kinase (GlpK) and the repressor for the glycerol 3-phosphate regulon (GlpR). When exposed to glycerol, it quickly accumulates lethal levels of methylglyoxal, which is a precursor of acetol;
Oxidation of glycerol and propanediols in methanol over heterogeneous gold catalysts.
Taarning E, et al.
Green Chemistry, 10(4), 408-414 (2008)
I Blank et al.
Advances in experimental medicine and biology, 561, 171-189 (2006-01-28)
The formation of acrylamide (AA) from L-asparagine was studied in Maillard model systems under pyrolysis conditions. While the early Maillard intermediate N-glucosylasparagine generated approximately 2.4 mmol/mol AA, the Amadori compound was a less efficient precursor (0.1 mmol/mol). Reaction with alpha-dicarbonyls
Junsang Ko et al.
Journal of bacteriology, 187(16), 5782-5789 (2005-08-04)
Methylglyoxal (MG) is a toxic metabolite known to accumulate in various cell types. We detected in vivo conversion of MG to acetol in MG-accumulating Escherichia coli cells by use of (1)H nuclear magnetic resonance ((1)H-NMR) spectroscopy. A search for homologs
Qi-Xiang Guo et al.
The Journal of organic chemistry, 77(7), 3589-3594 (2012-03-02)
The diastereoselectively switchable enantioselective Mannich reaction of isatin imines with hydroxyacetone is reported. The chiral primary amino acid catalyzed this Mannich reaction to afford both anti- and syn-Mannich adducts in high yields, good diastereoselectivities, and enantioselectivities. The reason for the

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