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142670

Sigma-Aldrich

Chloromethyl ethyl ether

95%

Synonym(s):
(Chloromethoxy)ethane, Ethoxychloromethane, Ethoxymethyl chloride, Ethyl chloromethyl ether
Linear Formula:
C2H5OCH2Cl
CAS Number:
Molecular Weight:
94.54
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

95%

form

liquid

refractive index

n20/D 1.404 (lit.)

bp

82 °C (lit.)

density

1.019 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CCOCCl

InChI

1S/C3H7ClO/c1-2-5-3-4/h2-3H2,1H3

InChI key

FCYRSDMGOLYDHL-UHFFFAOYSA-N

Application

Chloromethyl ethyl ether can be used to prepare:
  • 6-Benzyl-1-(ethoxymethyl)-5-iodopyrimidine-2,4(1H,3H)-dione, a key intermediate in the preparation of MKC-442 analog.
  • Acylation catalyst for alcohols named 1,3-bis-[(R)-1-(2-naphthyl)ethyl]imidazoliumchloride by reacting with glyoxal-bis-[(R)-1-(2-naphthyl)ethyl]imine.

Packaging

25 g in glass bottle
5 kg

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

66.2 °F - closed cup

Flash Point(C)

19 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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