14740

Sigma-Aldrich

N,N,N′,N′-Tetramethyl-1,3-butanediamine

≥99.0%

Synonym(s):
N,N,N,N′-Tetramethyl-1,3-diaminobutane, 1,3-Bis(dimethylamino)butane
Linear Formula:
(CH3)2NCH(CH3)CH2CH2N(CH3)2
CAS Number:
Molecular Weight:
144.26
Beilstein/REAXYS Number:
1698054
EC Number:
MDL number:
PubChem Substance ID:

vapor density

5 (vs air)

vapor pressure

1.64 mmHg ( 20 °C)

assay

≥99.0%

expl. lim.

7.8 %

refractive index

n20/D 1.431 (lit.)
n20/D 1.431

bp

165 °C (lit.)
55-56 °C/12 mmHg (lit.)

density

0.787 g/mL at 25 °C (lit.)

SMILES string

CC(CCN(C)C)N(C)C

InChI

1S/C8H20N2/c1-8(10(4)5)6-7-9(2)3/h8H,6-7H2,1-5H3

InChI key

AXFVIWBTKYFOCY-UHFFFAOYSA-N

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General description

N,N,N′,N′-Tetramethyl-1,3-butanediamine is an efficient electrolyte additive during the separation of tricyclic antidepressant by capillary zone electrophoresis.

Certificate of Analysis

Certificate of Origin

Caterina Dell'Aquila
Journal of pharmaceutical and biomedical analysis, 30(2), 341-350 (2002-08-23)
Five tricyclic antidepressants (TADs), desipramyne, nortriptyline, imipramine, doxepin and amitriptyline, were separated by using the N,N,N',N'-tetramethyl-1,3-butanediamine (TMBD) as additive in the background electrolyte solution. Because the tricyclic antidepressants are similar in structure, mass and pka values, their separation, by capillary...
D Corradini et al.
Electrophoresis, 16(4), 630-635 (1995-04-01)
The effect of N,N,N',N'-tetramethyl-1,3-butanediamine (TMBD) in the running electrolyte on the electroosmotic flow and the migration behavior of four standard basic proteins in bare fused-silica capillaries was examined at pH 4.0, 5.5, and 6.5. Depending on the electrolyte pH and...
D Corradini et al.
Electrophoresis, 17(1), 120-124 (1996-01-01)
The electrophoresis of epsilon-N-2-furoylmethyl-L-lysine (furosine) was studied in an attempt to develop a method for the identification and quantitation of this compound in processed food. The effect of pH and composition of electrolyte solution on both the electrophoretic migration of...

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