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MilliporeSigma

148938

2-Iodopropane

contains copper as stabilizer, 99%

Synonym(s):

Isopropyl iodide

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$37.90

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$51.30

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$174.00

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About This Item

Linear Formula:
(CH3)2CHI
CAS Number:
Molecular Weight:
169.99
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-859-3
Beilstein/REAXYS Number:
1098244
MDL number:
Assay:
99%
Form:
liquid

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InChI key

FMKOJHQHASLBPH-UHFFFAOYSA-N

InChI

1S/C3H7I/c1-3(2)4/h3H,1-2H3

SMILES string

CC(C)I

assay

99%

form

liquid

contains

copper as stabilizer

refractive index

n20/D 1.498 (lit.)

bp

88-90 °C (lit.)

mp

−90 °C (lit.)

density

1.703 g/mL at 25 °C (lit.)

functional group

alkyl halide, iodo

Quality Level

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1 of 4

This Item
342017603724687383
assay

99%

assay

98%

assay

≥99% (CP)

assay

≥98% (CP)

Quality Level

200

Quality Level

100

Quality Level

-

Quality Level

-

density

1.703 g/mL at 25 °C (lit.)

density

2.08 g/mL at 25 °C (lit.)

density

1.713 g/mL at 25 °C

density

-

mp

−90 °C (lit.)

mp

-

mp

-

mp

-

bp

88-90 °C (lit.)

bp

40 °C (lit.)

bp

88-90 °C (lit.)

bp

-

refractive index

n20/D 1.498 (lit.)

refractive index

n20/D 1.329 (lit.)

refractive index

-

refractive index

-

Application

2-Iodopropane (Isopropyl iodide) was used to prepare butyric and isobutyric acid[1].

2-Iodopropane is used as an alkylating agent in the conversion of phenols, alcohols, oximes, carboxylic acids, and heteroatomic compounds (indoles, pyridines, purines, tetrazoles, pyrazoles, and amines) to give corresponding products.[2]

General description

2-Iodopropane is an organ iodine compound. It is commonly used as a homolytic and heterolytic alkylating agent and in the preparation of the α-isopropoxymethylene blocking group. Additionally, it acts as an intermediator in the conversion of thiocarbonate to alkene.[2]

pictograms

FlameExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

107.6 °F - closed cup

flash_point_c

42 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Development and validation of analytical procedure--control of residual 2-iodopropane in latanoprost.
Aleksandra Groman et al.
Acta poloniae pharmaceutica, 67(6), 673-676 (2011-01-15)
John J Orlando et al.
The journal of physical chemistry. A, 109(30), 6659-6675 (2006-07-13)
The reaction of Cl atoms with iodoethane has been studied via a combination of laser flash photolysis/resonance fluorescence (LFP-RF), environmental chamber/Fourier transform (FT)IR, and quantum chemical techniques. Above 330 K, the flash photolysis data indicate that the reaction proceeds predominantly
W Kenealy et al.
Journal of bacteriology, 146(1), 133-140 (1981-04-01)
Iodopropane inhibited cell growth and methane production when Methanobacterium thermoautotrophicum, Methanobacterium formicicum, and Methanosarcina barkeri were cultured on H2-CO2. Iodopropane (40 microM) inhibited methanogenesis (30%) and growth (80%) when M. barkeri was cultured mixotrophically on H2-CO2-methanol. The addition of acetate
Timur Coskun et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 19(21), 6840-6844 (2013-03-29)
Glycerol is converted to a mixture of butyric and isobutyric acid by rhodium- or iridium-catalysed carbonylation using HI as the co-catalyst. The initial reaction of glycerol with HI results in several intermediates that lead to isopropyl iodide, which upon carbonylation
Joe Rashan et al.
Journal of AOAC International, 86(4), 694-702 (2003-09-26)
An alternative liquid chromatographic (LC) method was developed and validated for the simultaneous determination of methoxyl and 2-hydroxypropoxyl substituents in hypromellose and hypromellose acetate succinate. The method uses the hydriodic acid cleavage reaction, catalyzed by adipic acid, of the substituted

Questions

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    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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