2,5-Dihydroxybenzoic acid


Gentisic acid, 2,5-DHBA, DHB, Hydroquinonecarboxylic acid
Linear Formula:
CAS Number:
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Quality Level




204-208 °C (lit.)

SMILES string




InChI key


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General description

Aspirin metabolite.


2,5-Dihydroxybenzoic acid (2,5-DHBA) can be used:
  • As a matrix in the MALDI-TOF mass spectrometry analysis of the poly(styrene-co-pentafluorostyrene) copolymers.
  • To prepare pharmacologically important 2,5-DBHA-gelatin conjugate, which can act as a polymer for the development of drug formulations.
  • As a tridentate ligand to synthesize complexes of molybdenum by reacting with (PPh4)4Mo8O26.
  • As a starting material in the total synthesis of landomycin A, an angucycline antibiotic.


10, 25, 100 g in poly bottle

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Polynuclear oxomolybdenum (VI) complexes of dihydroxybenzoic acids: Synthesis, spectroscopic and structure characterization of a tetranuclear catecholato-type coordinated 2, 3-dihydroxybenzoate and a novel tridentate salicylato-type coordinated 2, 5-dihydroxybenzoate trinuclear complex
Litos C, et al.
Polyhedron, 25(6), 1337-1347 (2006)
Matrix-assisted laser desorption/ionization sample preparation optimization for structural characterization of poly (styrene-co-pentafluorostyrene) copolymers
Tisdale E, et al.
Analytica Chimica Acta, 808, 151-162 (2014)
Evgenia Tisdale et al.
Analytica chimica acta, 808, 151-162 (2013-12-29)
The influence of the sample preparation parameters (the choice of the matrix, matrix:analyte ratio, salt:analyte ratio) was investigated and optimal conditions were established for the MALDI time-of-flight mass spectrometry analysis of the poly(styrene-co-pentafluorostyrene) copolymers. These were synthesized by atom transfer...
A 2, 5-Dihydroxybenzoic acid-gelatin conjugate: the synthesis, antiviral activity and mechanism of antiviral action against two alphaherpesviruses
Lisov A, et al.
Viruses, 7(10), 5343-5360 (2015)
Xiaoyu Yang et al.
Journal of the American Chemical Society, 133(32), 12433-12435 (2011-07-26)
The first total synthesis of landomycin A, the longest and most potent antitumor angucycline antibiotic, has been achieved in 63 steps and 0.34% overall yield starting from 2,5-dihydroxybenzoic acid, 3,5-dimethylphenol, triacetyl d-glucal, and d-xylose, with a convergent linear sequence of...

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