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MilliporeSigma

150215

9(10H)-Acridanone

99%

Synonym(s):

Acridone, 9,10-Dihydro-9-oxoacridine

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About This Item

Empirical Formula (Hill Notation):
C13H9NO
CAS Number:
578-95-0
Molecular Weight:
195.22
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24848848
EC Number:
209-434-7
Beilstein/REAXYS Number:
7104
MDL number:
MFCD00005019
Assay:
99%
Form:
solid

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InChI key

FZEYVTFCMJSGMP-UHFFFAOYSA-N

InChI

1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15)

SMILES string

O=C1c2ccccc2Nc3ccccc13

assay

99%

form

solid

mp

>300 °C (lit.)

λmax

380 nm, 399 nm (2nd)

Quality Level

100

Gene Information

human ... ABCB1(5243)

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1 of 4

This Item
17927775525252727
9(10H)-Acridanone 99%

Sigma-Aldrich

150215

9(10H)-Acridanone

9-Oxo-10(9H)-acridineacetic acid derivatization grade (HPLC), ≥99.0% (T)

Sigma-Aldrich

17927

9-Oxo-10(9H)-acridineacetic acid

Acridine-9-carboxaldehyde 97%

Sigma-Aldrich

775525

Acridine-9-carboxaldehyde

Anthraquinone-2-carboxylic acid 98%

Sigma-Aldrich

252727

Anthraquinone-2-carboxylic acid

assay

99%

assay

≥99.0% (T)

assay

97%

assay

98%

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mp

>300 °C (lit.)

mp

~289 °C (dec.)

mp

144-149 °C

mp

287-289 °C (lit.)

form

solid

form

solid

form

solid

form

solid

λmax

380 nm

λmax

-

λmax

-

λmax

-

Gene Information

human ... ABCB1(5243)

Gene Information

-

Gene Information

-

Gene Information

-

Application

9(10H)-Acridanone (acridone) was used in the preparation of methyl 9,10-dihydro-9-oxoacridine-10-pentanoate[1].

related product

Product No.
Description
Pricing

906115

2,7-Dibromoacridone

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV9083
MKCR2220
MKCQ6082
MKCQ0531
MKCN1370

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Giuseppe Manfroni et al.
Journal of medicinal chemistry, 52(10), 3354-3365 (2009-04-25)
We report the synthesis and structure-activity relationship (SAR) of a large series of acridones and acridone-fragment derivatives designed on the basis of the selective antihepatitis C virus (HCV) activity shown by acridone 2, previously studied as a potential antibovine viral
Dadi Chen et al.
Biotechnology for biofuels, 13, 130-130 (2020-07-24)
Considerable interest has been expressed in the development of anaerobic digestion (AD) of straw to solve the environmental problems caused by the dumping and burning of straw and to generate clean energy. However, the poor biodegradability of straw and the
Emerson F Marques et al.
European journal of medicinal chemistry, 54, 10-21 (2012-05-18)
Cathepsins, also known as lysosomal cysteine peptidases, are members of the papain-like peptidase family, involved in different physiological processes. In addition, cathepsins are implicated in many pathological conditions. This report describes the synthesis and evaluation of a series of N-arylanthranilic
Richele P Severino et al.
Bioorganic & medicinal chemistry, 19(4), 1477-1481 (2011-02-01)
Cathepsin V is a lysosomal cysteine peptidase highly expressed in thymus, testis and corneal epithelium. Eleven acridone alkaloids were isolated from Swinglea glutinosa (Bl.) Merr. (Rutaceae), with eight of them being identified as potent and reversible inhibitors of cathepsin V
Florian Astelbauer et al.
Vector borne and zoonotic diseases (Larchmont, N.Y.), 11(7), 793-798 (2011-03-23)
Visceral and cutaneous leishmaniases are an important public health problem in endemic geographic regions in 88 countries worldwide, with around 12 million infected people. Treatment options are limited due to toxicity and teratogenicity of the available drugs, response problems in
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