208. The reaction between phenylhydrazine and 4-chloroquinoline derivatives, and the preparation of the corresponding 4-benzeneazo-and 4-amino-compounds.
Journal of the Chemical Society, 1083-1087 (1938)
K N Vennila et al.
Bioorganic chemistry, 81, 184-190 (2018-08-24)
The induced fit docking of anilino quinoline scaffold results in the required hydrogen bonding interactions with amino acid residues in the orthosteric site of 3 Phosphoinositide dependent kinase (PDK1). The rational design of 4-substituted amino quinolines is carried out and...