All Photos(1)

15381

Sigma-Aldrich

Boc-Asn-OH

≥98.5% (T)

Synonym(s):
Boc-L-asparagine, Nα-(tert-Butoxycarbonyl)-L-asparagine
Linear Formula:
NH2COCH2CH(COOH)NHC(O)OC(CH3)3
CAS Number:
Molecular Weight:
232.23
Beilstein:
1977963
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

≥98.5% (T)

optical activity

[α]20/D −7.8±0.5°, c = 2% in DMF

reaction suitability

reaction type: Boc solid-phase peptide synthesis

ign. residue

≤0.2%

mp

175 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)(C)OC(=O)N[C@@H](CC(N)=O)C(O)=O

InChI

1S/C9H16N2O5/c1-9(2,3)16-8(15)11-5(7(13)14)4-6(10)12/h5H,4H2,1-3H3,(H2,10,12)(H,11,15)(H,13,14)/t5-/m0/s1

InChI key

FYYSQDHBALBGHX-YFKPBYRVSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Wei Jiang et al.
Molecular immunology, 119, 8-17 (2020-01-14)
Motile sperm domain containing 2 (MOSPD2) is a single-pass membrane protein to which until recently little function had been ascribed. Although its mammalian homologs have been identified, the status of the mospd2 gene in lower vertebrates is still unknown. In
Laura D'Ignazio et al.
International journal of molecular sciences, 21(8) (2020-04-30)
NF-κB signalling is crucial for cellular responses to inflammation but is also associated with the hypoxia response. NF-κB and hypoxia inducible factor (HIF) transcription factors possess an intense molecular crosstalk. Although it is known that HIF-1α modulates NF-κB transcriptional response
Fei Huang et al.
Experimental cell research, 374(1), 94-103 (2018-11-21)
Hypoxia frequently occurs in solid tumors, hepatocellular carcinoma included. Hypoxia-inducible factors (HIFs) upregulated in hypoxia can induce various downstream target genes to resist hypoxia stress, resulting in tumor growth, angiogenesis and metastasis in vivo. Therefore, hypoxia associated genes are usually
Timothy J Hark et al.
Cell systems, 12(2), 141-158 (2020-12-17)
Compromised protein homeostasis underlies accumulation of plaques and tangles in Alzheimer's disease (AD). To observe protein turnover at early stages of amyloid beta (Aβ) proteotoxicity, we performed pulse-chase proteomics on mouse brains in three genetic models of AD that knock
Jan Kristoff et al.
EBioMedicine, 43, 295-306 (2019-04-07)
Despite the success of antiretroviral therapy (ART), latent HIV-1 continues to persist in a long-lived population of resting memory CD4+ T cells within those who are infected. Finding a safe and effective means to induce latency reversal (LR) during ART

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