155225

Sigma-Aldrich

2-Piperidinemethanol

97%

Synonym(s):
2-(Hydroxymethyl)piperidine
Empirical Formula (Hill Notation):
C6H13NO
CAS Number:
Molecular Weight:
115.17
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

97%

mp

68-70 °C (lit.)

SMILES string

OCC1CCCCN1

InChI

1S/C6H13NO/c8-5-6-3-1-2-4-7-6/h6-8H,1-5H2

InChI key

PRAYXGYYVXRDDW-UHFFFAOYSA-N

Application

2-Piperidinemethanol was used in the synthesis of 3-phenyloctahydropyrido[2,1-c][1,4]oxazine hydrochloride and the 10R and 10S diastereomers.

Packaging

5, 25, 100 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Daniel C O'Brien et al.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 163(3), 508-516 (2020-05-27)
To assess the exposure of surgical personnel to known carcinogens during pediatric tonsillectomy and adenoidectomy (T&A) and compare the efficacy of surgical smoke evacuation systems during T&A. Prospective, case series. Tertiary children's hospital. The present study assessed operating room workers'...
Mostafa Hadei et al.
Journal of occupational medicine and toxicology (London, England), 13, 30-30 (2018-10-03)
The use of cosmetic products in beauty salons emits numerous kinds of toxic air pollutants. The objectives of this study were to measure the concentrations of benzene, toluene, ethylbenzene, xylene, formaldehyde, and acetaldehyde in 20 large beauty salons in Tehran...
T N Riley et al.
Journal of medicinal chemistry, 19(2), 334-336 (1976-02-01)
3-Phenyloctahydropyrido[2,1-c][1,4]oxazine hydrochloride and the 10R and 10S diastereomers have been synthesized from (+/-)-, (+)-, and (-)-2-piperidinemethanol. Treatment of 2-piperidinemethanol with alpha-bromoacetophenone gave 3-hydroxy-3-phenyloctahydropyrido[2,1-c][1,4]oxazine which was readily converted to the 3-phenyl derivative by catalytic hydrogenolysis. These compounds were shown to possess...

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