156140

o-Phenylene phosphorochloridate

technical grade

• Synonym(s): 2-Chloro-1,3,2-benzodioxaphosphole 2-oxide, o-Phenylene chlorophosphate, Catechol cyclophosphorochloridate
• Empirical Formula (Hill Notation): C₆H₄ClO₃P
• CAS Number: 1499-17-8
• Molecular Weight: 190.52
• Beilstein: 142368
• EC Number: 216-106-7
• MDL number: MFCD00005854
• PubChem Substance ID: 24849594
• NACRES: NA.22

Properties

• grade: technical grade
• form: solid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling
• bp: 120 °C/9 mmHg (lit.)
• SMILES string: ClP1(=O)Oc2ccccc2O1
• InChI: 1S/C6H4ClO3P/c7-11(8)9-5-3-1-2-4-6(5)10-11/h1-4H
• InChI key: KMWSGKPLIWNTEF-UHFFFAOYSA-N

Description

Application

Reactant for preparation of:

• Uridine diphosphate-glucose derivatives as potential chain terminators of β-glucan biosynthesis with antifungal activity
• Vinyloxy phosphorus monomers

• Phosphorylation agent

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363
• Hazard Classifications: Skin Corr. 1B
• Supplementary Hazards: EUH014
• Storage Class Code: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves