158615

Tributyl phosphate

97%

• Synonym(s): TBP, TBPA
• Linear Formula: (CH₃(CH₂)₃O)₃PO
• CAS Number: 126-73-8
• Molecular Weight: 266.31
• Beilstein/REAXYS Number: 1710584
• EC Number: 204-800-2
• MDL number: MFCD00009436
• UNSPSC Code: 12352100
• PubChem Substance ID: 24849766
• NACRES: NA.22

Properties

• vapor density: 9.2 (vs air)
• Quality Level: 300
• vapor pressure: 27 mmHg ( 178 °C); 7.3 mmHg ( 150 °C)
• assay: 97%
• form: liquid
• autoignition temp.: 770 °F
• refractive index: n20/D 1.424 (lit.)
• bp: 180-183 °C/22 mmHg (lit.)
• mp: −79 °C (lit.)
• solubility: water: soluble 1ml in 165ml water; organic solvents: miscible
• density: 0.979 g/mL at 25 °C (lit.)
• functional group: phosphate
• SMILES string: CCCCOP(=O)(OCCCC)OCCCC
• InChI: 1S/C12H27O4P/c1-4-7-10-14-17(13,15-11-8-5-2)16-12-9-6-3/h4-12H2,1-3H3
• InChI key: STCOOQWBFONSKY-UHFFFAOYSA-N

Description

General description

Tributyl phosphate (TBP) is an organophosphorus compound widely used as a solvent in nuclear fuel reprocessing for the extraction of uranium and plutonium from other radionuclides.[1][2]

Tributyl phosphate is an endocrine disrupting compound.[3]

Application

Tributyl phosphate was employed as:

• solvent in the solvent-detergent method for production of immunoglobulin for inactivation of viruses with lipid envelope on the model of duck hepatitis B virus[4]
• ligand in the extraction of lanthanide ions from solid and liquid materials by supercritical CO₂[5]
• extractant for metal complexes[6]

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H315,H351,H412
• pcodes: P202 - P264 - P273 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Skin Irrit. 2
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 2
• flash_point_f: 293.0 °F - closed cup
• flash_point_c: 145 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter