159506

Sigma-Aldrich

4-Tritylaniline

97%

Synonym(s):
4-Triphenylmethylaniline
Linear Formula:
(C6H5)3CC6H4NH2
CAS Number:
Molecular Weight:
335.44
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

97%

mp

255-257 °C (lit.)

SMILES string

Nc1ccc(cc1)C(c2ccccc2)(c3ccccc3)c4ccccc4

InChI

1S/C25H21N/c26-24-18-16-23(17-19-24)25(20-10-4-1-5-11-20,21-12-6-2-7-13-21)22-14-8-3-9-15-22/h1-19H,26H2

InChI key

XYHDHXBLSLSXSR-UHFFFAOYSA-N

Related Categories

General description

4-Tritylaniline is also referred as p-tritylaniline.

Application

4-Tritylaniline was used in the preparation of:
  • 5-tritylisatin
  • 2,7-di-tert-butyl-9,9-dimethyl-4,5-bis(4-tritylanilinocarbonyl)-9H-xanthene methanol trisolvate monohydrate
  • bis-4,4-6-chloro-N-(4-tritylphenyl)-1,3,5triazine-2,4-diamine-2,2-disulfonic acid-stilbene, novel fluorophore, with potential application as an optical brightener

Packaging

5 g in glass bottle

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xi

Risk Statement

36/37/38

Safety Statement

26-37/39

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Synthesis of a Fluorophore with Improved Optical Brightness.
Okuom M, et al.
International Journal of Organic Chemistry (2013)
Larry L Klein et al.
Tetrahedron letters, 54(8), 1008-1011 (2013-03-08)
Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules and identified an...
2, 7-Di-tert-butyl-9, 9-dimethyl-4, 5-bis (4-tritylanilinocarbonyl)-9H-xanthene methanol trisolvate monohydrate.
Vysotsky MO and Schollmeyer D.
Acta Crystallographica Section E, Structure Reports Online, 63(1), o169-o171 (2006)
Salvatore Debonis et al.
Journal of medicinal chemistry, 51(5), 1115-1125 (2008-02-13)
The human kinesin Eg5 is a potential drug target for cancer chemotherapy. Eg5 specific inhibitors cause cells to block in mitosis with a characteristic monoastral spindle phenotype. Prolonged metaphase block eventually leads to apoptotic cell death. S-trityl-L-cysteine (STLC) is a...

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