161810

Sigma-Aldrich

5-Chloro-2-methylene-1,3,3-trimethylindoline

technical grade, 95%

Empirical Formula (Hill Notation):
C12H14ClN
CAS Number:
Molecular Weight:
207.70
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

grade

technical grade

Quality Level

assay

95%

refractive index

n20/D 1.594 (lit.)

density

1.083 g/mL at 25 °C (lit.)

SMILES string

CN1C(=C)C(C)(C)c2cc(Cl)ccc12

InChI

1S/C12H14ClN/c1-8-12(2,3)10-7-9(13)5-6-11(10)14(8)4/h5-7H,1H2,2-4H3

InChI key

VDMXGJJMPKAYQP-UHFFFAOYSA-N

General description

5-Chloro-2-methylene-1,3,3-trimethylindoline undergoes regiospecific 1,3-dipolar cycloaddition reaction with arylnitriloxydes and N-phenylarylnitrilimines.

Application

5-Chloro-2-methylene-1,3,3-trimethylindoline was used in the synthesis of 5′,6-dichloro-1′,3′,3′-trimethyl­spiro­2H-1-benzopyran-2,2′-indoline.

Packaging

25 g in glass bottle

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

Xi

Risk Statement

36/37/38

Safety Statement

26-37/39

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Nameer Alhashimy et al.
Acta crystallographica. Section E, Structure reports online, 64(Pt 8), o1430-o1431 (2008-01-01)
In the crystal structure of the title compound, C(19)H(17)Cl(2)NO, the indoline and benzopyran ring systems are approximately perpendicular to each other. The indoline ring is in an envelope conformation with the spiro C atom as the flap. The N atom...
Naoual Laghrib et al.
Acta crystallographica. Section E, Structure reports online, 65(Pt 2), o374-o374 (2009-01-01)
Two diastereoisomers of the title compound, C(25)H(26)N(2)O, have been prepared by cyclo-addition between 1,3,3-trimethyl-2-methyl-eneindoline and C-phenyl-N-phenyl-nitrone. The stereochemistry of the major diastereoisomer, viz. S,R/R,S, is confirmed by the X-ray analysis. The oxazole and the pyrole rings have envelope conformations. The...

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