162701

Sigma-Aldrich

2-(Chloromethyl)pyridine hydrochloride

98%

Synonym(s):
2-Picolyl chloride hydrochloride
Empirical Formula (Hill Notation):
C6H6ClN · HCl
CAS Number:
Molecular Weight:
164.03
Beilstein/REAXYS Number:
3689155
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

98%

mp

120-124 °C (lit.)

SMILES string

ClH.ClCc1ccccn1

InChI

1S/C6H6ClN.ClH/c7-5-6-3-1-2-4-8-6;/h1-4H,5H2;1H

InChI key

JPMRGPPMXHGKRO-UHFFFAOYSA-N

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Application

2-(Chloromethyl)pyridine hydrochloride was used as reagent in base catalyzed alkylation of p-tert-butylcalix6arene and p-tert-butylcalix5arene in DMF. It was used in the synthesis of Gd3+ diethylenetriaminepentaacetic acid bisamide complex, a Zn2+-sensitive magnetic resonance imaging contrast agent.

Packaging

5, 25, 100 g in glass bottle

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

C

Risk Statement

22-34

Safety Statement

26-36/37/39-45

RIDADR

UN 3261 8 / PGIII

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Functionalization of p-tert-butylcalix [6] arene by alkylation with 2-(chloromethyl) pyridine hydrochloride.
Neri P and Pappalardo S.
The Journal of Organic Chemistry, 58(5), 1048-1053 (1993)
Selective sensing of zinc ions with a novel magnetic resonance imaging contrast agent.
Hanaoka K, et al.
J. Chem. Soc. Perkin Trans. II, 9, 1840-1843 (2001)
Functionalization of p-tert-Butylcalix [5] arene by Alkylation with 2-(Chloromethyl) pyridine Hydrochloride.
Pappalardo S and Ferguson G.
The Journal of Organic Chemistry, 61(7), 2407-2412 (1996)
M Batiste-Alentorn et al.
Mutation research, 341(3), 161-167 (1995-01-01)
To provide further background data for the somatic mutation and/or recombination tests in Drosophila melanogaster, we have evaluated the response in 3 assays (zeste-white, white-ivory and wing spot) of 5 chemicals classified by the U.S. National Toxicology Program (NTP) as...
Alexander R Parent et al.
Dalton transactions (Cambridge, England : 2003), 43(33), 12501-12513 (2014-07-09)
Iron tris(2-methylpyridyl)amine (TPA) and iron 1-(bis(2-methylpyridyl)amino)-2-methyl-2-propanoate (BPyA) salts are characterized as water oxidation catalysts (WOCs) using sodium periodate. Under the conditions used, these complexes serve as homogeneous WOCs as demonstrated via kinetic analysis and dynamic light scattering (DLS). The Fe(BPyA)...

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