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162701

2-(Chloromethyl)pyridine hydrochloride

98%

Synonym(s):

2-Picolyl chloride hydrochloride

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Pack SizeSKUAvailabilityPrice
5 g

Estimated to ship onMay 06, 2026fromMILWAUKEE

$67.60
25 g

Estimated to ship onMay 04, 2026fromMILWAUKEE

$113.00
100 g

Available to ship onApril 07, 2026fromMILWAUKEE

$148.00

About This Item

Empirical Formula (Hill Notation):
C6H6ClN · HCl
CAS Number:
Molecular Weight:
164.03
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
230-149-9
Beilstein/REAXYS Number:
3689155
MDL number:
Assay:
98%
Form:
solid

$67.60


Estimated to ship onMay 06, 2026Details


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Quality Level

assay

98%

form

solid

mp

120-124 °C (lit.)

functional group

chloro

SMILES string

Cl[H].ClCc1ccccn1

InChI

1S/C6H6ClN.ClH/c7-5-6-3-1-2-4-8-6;/h1-4H,5H2;1H

InChI key

JPMRGPPMXHGKRO-UHFFFAOYSA-N

Application

2-(Chloromethyl)pyridine hydrochloride was used as reagent in base catalyzed alkylation of p-tert-butylcalix[6]arene and p-tert-butylcalix[5]arene in DMF. It was used in the synthesis of Gd3+ diethylenetriaminepentaacetic acid bisamide complex, a Zn2+-sensitive magnetic resonance imaging contrast agent.

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assay

98%

assay

97%

assay

96%

assay

98%

Quality Level

200

Quality Level

100

Quality Level

-

Quality Level

200

form

solid

form

powder

form

solid

form

powder

mp

120-124 °C (lit.)

mp

166-173 °C (lit.)

mp

137-143 °C (lit.)

mp

187-190 °C (lit.)

functional group

chloro

functional group

-

functional group

-

functional group

-


pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Functionalization of p-tert-Butylcalix [5] arene by Alkylation with 2-(Chloromethyl) pyridine Hydrochloride.
Pappalardo S and Ferguson G.
The Journal of Organic Chemistry, 61(7), 2407-2412 (1996)
Functionalization of p-tert-butylcalix [6] arene by alkylation with 2-(chloromethyl) pyridine hydrochloride.
Neri P and Pappalardo S.
The Journal of Organic Chemistry, 58(5), 1048-1053 (1993)
Selective sensing of zinc ions with a novel magnetic resonance imaging contrast agent.
Hanaoka K, et al.
J. Chem. Soc. Perkin Trans. II, 9, 1840-1843 (2001)



Global Trade Item Number

SKUGTIN
162701-25G04061838747181
162701-100G04061838747174
162701-5G04061838747198

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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