175277

Sigma-Aldrich

2H-1,4-Benzothiazin-3(4H)-one

97%

Empirical Formula (Hill Notation):
C8H7NOS
CAS Number:
Molecular Weight:
165.21
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

Quality Level

assay

97%

mp

176-178 °C (lit.)

SMILES string

O=C1CSc2ccccc2N1

InChI

1S/C8H7NOS/c10-8-5-11-7-4-2-1-3-6(7)9-8/h1-4H,5H2,(H,9,10)

InChI key

GTFMIJNXNMDHAB-UHFFFAOYSA-N

General description

2H-1,4-Benzothiazin-3(4H)-one derivatives were synthesized and tested for calcium antagonistic and calmodulin antagonistic activities.

Packaging

25 g in glass bottle

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

M Kajino et al.
Chemical & pharmaceutical bulletin, 39(11), 2888-2895 (1991-11-01)
New 2H-1,4-benzothiazin-3(4H)-one derivatives possessing (4-phenyl-1-piperazinyl)alkyl moieties at the 2-position were synthesized and tested for calcium antagonistic and calmodulin antagonistic activities. Antihypertensive effects in spontaneously hypertensive rats were also evaluated. In general, these compounds were rather weak calcium channel blockers, although...

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