Synthesis of an O-alkynyl-chitosan and its chemoselective conjugation with a PEG-like amino-azide through click chemistry.
Carbohydrate Polymers, 87(1), 240-249 (2012)
Claudia Arndt et al.
Oncoimmunology, 8(11), 1659095-1659095 (2019-10-28)
Chimeric antigen receptor (CAR) T cells have shown impressive therapeutic potential. Due to the lack of direct control mechanisms, therapy-related adverse reactions including cytokine release- and tumor lysis syndrome can even become life-threatening. In case of target antigen expression on...
Controlled folding of polystyrene single chains: design of asymmetric covalent bridges.
Polym. Chem., 3(7), 1796-1802 (2012)
C.R. Bertozzi et al.
The Journal of Organic Chemistry, 56, 4326-4326 (1991)
Brittany L Hartwell et al.
Journal of autoimmunity, 93, 76-88 (2018-07-17)
Autoreactive lymphocytes that escape central immune tolerance may be silenced via an endogenous peripheral tolerance mechanism known as anergy. Antigen-specific therapies capable of inducing anergy may restore patients with autoimmune diseases to a healthy phenotype while avoiding deleterious side effects...