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185892
Ethyl chloroformate
97%
Synonym(s):
Chloroformic acid ethyl ester
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$43.40
$47.30
$203.00
$477.00
$43.40
About This Item
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InChI key
RIFGWPKJUGCATF-UHFFFAOYSA-N
InChI
1S/C3H5ClO2/c1-2-6-3(4)5/h2H2,1H3
SMILES string
CCOC(Cl)=O
vapor density
3.74 (vs air)
vapor pressure
3.42 psi ( 20 °C)
assay
97%
form
liquid
autoignition temp.
842 °F
refractive index
n20/D 1.395 (lit.)
bp
93 °C (lit.)
mp
−81 °C (lit.)
solubility
alcohol: miscible, benzene: miscible, chloroform: miscible, diethyl ether: miscible, water: insoluble
density
1.135 g/mL at 25 °C (lit.)
functional group
chloro
Quality Level
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Related Categories
1 of 4
This Item | 177989 | 12990 | 12980 |
|---|---|---|---|
| assay 97% | assay 98% | assay ≥95% (HPLC) | assay ≥97.0% (HPLC) |
| Quality Level 200 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| solubility alcohol: miscible, chloroform: miscible, water: insoluble, benzene: miscible, diethyl ether: miscible | solubility benzene: miscible, chloroform: miscible, diethyl ether: miscible | solubility H2O: insoluble, alcohol: miscible, diethyl ether: miscible | solubility H2O: insoluble, alcohol: miscible, diethyl ether: miscible |
| form liquid | form liquid | form liquid | form - |
| refractive index n20/D 1.395 (lit.) | refractive index n20/D 1.407 (lit.) | refractive index n20/D 1.52 (lit.), n20/D 1.520-1.540 | refractive index n20/D 1.52 (lit.), n20/D 1.531 |
| density 1.135 g/mL at 25 °C (lit.) | density 1.053 g/mL at 25 °C (lit.) | density 1.11 g/mL at 25 °C (lit.) | density 1.11 g/mL at 25 °C (lit.) |
Application
- Ethyl chloroformate was used in the synthesis of nitrile oxides[1].
- It was used as derivatization reagent to investigate stereochemical conversion of chiral non-steroidal anti-inflammatory drugs during derivatization reaction[2].
- It was used to develop flexible template strategy for the generation of nanometer-scale templates via dip-pen nanolithography[3].
- It was used as derivatization reagent in an enantiomeric analysis of amino acids by two-dimensional gas chromatography[4].
- It was also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles[5].
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Met. Corr. 1 - Skin Corr. 1B
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
60.8 °F
flash_point_c
16 °C
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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