187070

Sigma-Aldrich

2-Bromobenzyl bromide

98%

Synonym(s):
α,2-Dibromotoluene
Linear Formula:
BrC6H4CH2Br
CAS Number:
Molecular Weight:
249.93
Beilstein/REAXYS Number:
971015
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

98%

refractive index

n20/D 1.619 (lit.)

bp

129 °C/19 mmHg (lit.)

mp

29-32 °C (lit.)

solubility

dioxane: soluble 1 g/10 mL, clear, colorless

SMILES string

BrCc1ccccc1Br

InChI

1S/C7H6Br2/c8-5-6-3-1-2-4-7(6)9/h1-4H,5H2

InChI key

LZSYGJNFCREHMD-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

2-Bromobenzyl bromide was used in the synthesis of:
  • substituted quinazolines and 1,2,3,4-tetrahydroquinazolines
  • 2- and 3-substituted indenes
  • tris-2-bromotribenzylamine

Packaging

25, 100 g in glass bottle

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

UN 3261 8 / PGIII

WGK Germany

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Synthesis and structural studies of tris-2-chlorobenzylamine and tris-2-bromobenzylamine.
Chen Q, , et al.
Journal of Chemical Crystallography, 35(3), 177-181 (2005)
Efficient synthesis of 2-and 3-substituted indenes from 2-bromobenzyl bromide through an enolate alkylation/Cr (II)/Ni (II)-mediated carbonyl addition sequence.
Halterman RLand Zhu C.
Tetrahedron Letters, 40(42), 7445-7448 (1999)
Xuesen Fan et al.
Chemistry, an Asian journal, 9(3), 739-743 (2014-01-01)
An efficient synthesis of diversely substituted quinazolines and 1,2,3,4-tetrahydroquinazolines through copper-catalyzed tandem reactions of the readily available 2-bromobenzyl bromides, aldehydes, and aqueous ammonia or amines has been developed. By using ammonia and simple aliphatic amines as the nitrogen source, the...
Prachi Singh et al.
SLAS discovery : advancing life sciences R & D, 22(4), 440-446 (2017-03-23)
Analysis of interactions between molecules is of fundamental importance in life science research. In this study, we applied weak affinity chromatography, based on high-performance liquid chromatography and mass spectrometry, as a powerful tool for direct analysis of the components of...
William L Scott et al.
Journal of combinatorial chemistry, 11(1), 14-33 (2008-12-25)
Distributed Drug Discovery (D(3)) proposes solving large drug discovery problems by breaking them into smaller units for processing at multiple sites. A key component of the synthetic and computational stages of D(3) is the global rehearsal of prospective reagents and...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.