191744

Sigma-Aldrich

3-Methyl-1-phenyl-2-phospholene 1-oxide

85%, technical grade

Synonym(s):
NSC 107634, 2,3-Dihydro-4-methyl-1-phenylphosphole 1-oxide, 1-Oxo-3-methyl-1-phenyl-2-phospholene, MPPO
Empirical Formula (Hill Notation):
C11H13OP
CAS Number:
Molecular Weight:
192.19
MDL number:
PubChem Substance ID:
NACRES:
NA.22
Pricing and availability is not currently available.

grade

technical grade

assay

85%

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

impurities

5% dichloromethane

refractive index

n20/D 1.5707 (lit.)

bp

150 °C/0.15 mmHg (lit.)

functional group

phosphine

SMILES string

CC1=CP(=O)(CC1)c2ccccc2

InChI

1S/C11H13OP/c1-10-7-8-13(12,9-10)11-5-3-2-4-6-11/h2-6,9H,7-8H2,1H3

InChI key

YMKWWHFRGALXLE-UHFFFAOYSA-N

Application

Catalyst for:
  • Intramolecular aza-Wittig cyclization reactions
  • Polymerization reactions

Reactant for preparation of:
  • Phospha sugars and their radical bromination derivatives as anticancer agents

Packaging

10 g in glass bottle

Pictograms

Exclamation markHealth hazard

Signal Word

Warning

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Phuong-Mai Nguyen et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(10), 1703-1720 (2017-04-05)
Migration due to indirect contact with packaging caused several major sanitary crises, including the spread contamination of dry food by mineral oils and printing ink constituents from cardboard. The issues are still not fully resolved because the mechanisms have been...
Andrea Walzl et al.
Molecules (Basel, Switzerland), 25(15) (2020-08-06)
The current demand to cut back on the use of plastic materials has brought a major boost to the search for bio-based alternatives. Not only are plastic bags and primary food packaging under scrutiny here, but also those materials used...

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