Skip to Content
MilliporeSigma

Key Documents

View All Documentation

Skip To

191884

Hydroxypropyl cellulose

average Mw ~100,000, powder, 20 mesh particle size (99% through)

Synonym(s):

Cellulose & cellulose derivatives

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice
5 g

Available to ship TODAYfromMILWAUKEE

$72.40
100 g

Available to ship TODAYfromMILWAUKEE

$185.00
250 g

Available to ship TODAYfromMILWAUKEE

$358.00

About This Item

CAS Number:
9004-64-2
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
MFCD00132688

$72.40

Available to ship TODAYDetails

​
Request a Bulk Order
​
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

description

biological oxygen demand (BOD) 14,000 ppm

Quality Segment

200

form

powder

autoignition temp.

752 °F

mol wt

average Mw ~100,000

impurities

<5 wt. %

particle size

20 mesh (99% through)

pH

5.0-8.5

interfacial tension mineral oil

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

viscosity

65-175 cP, 5 wt. % in H2O(25 °C, Brookfield, spindle #1) (30 rpm)(lit.)

solubility

polar organic solvents: soluble

density

0.5 g/mL at 25 °C (lit.)

SMILES string

N(C)(C)c1cc(c(cc1)C(N)CC)C

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChI key

RRHXDYJWVYFMKV-UHFFFAOYSA-N

General description

Hydroxypropyl cellulose (HPC) is a neutral polysaccharide prepared by reacting propylene oxide with alkali cellulose at high temperatures and pressure. It is soluble in water and many polar organic solvents. HPC is widely used as a food additive and in drug delivery systems.

Application

Hydroxypropyl cellulose can be used in the following applications:
  • HPC is soluble in organic solvents which makes it suitable for the preparation of polymer gel electrolytes for electrochemical devices. The network-forming ability of HPC can improve the mechanical and electrical properties of gel electrolytes.
  • Electrospun hydroxypropyl cellulose nanofibres can be used to develop drug delivery systems for a variety of hydrophobic drugs.
  • Hydroxypropylcellulose combined with an effervescent agent like sodium carbonate can be usedas a binder and functional material to prepare floating tablets for thecontrolled release of ofloxacin.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
1918921919061329800
Hydroxypropyl cellulose average Mw ~100,000, powder, 20&#160;mesh particle size (99% through)

Sigma-Aldrich

191884

Hydroxypropyl cellulose

Hydroxypropyl cellulose average Mw ~370,000, powder, 20&#160;mesh particle size (99% through)

Sigma-Aldrich

191892

Hydroxypropyl cellulose

Hydroxypropyl cellulose average Mw ~1,000,000, powder, 20&#160;mesh particle size (99% through)

Sigma-Aldrich

191906

Hydroxypropyl cellulose

Hydroxypropyl cellulose United States Pharmacopeia (USP) Reference Standard

USP

1329800

Hydroxypropyl cellulose

viscosity

65-175 cP, 5 wt. % in H2O(25 °C, Brookfield, spindle #1) (30 rpm)(lit.)

viscosity

150-400 cP, 2 wt. % in H2O(25 °C, Brookfield, spindle #2) (60 rpm)(lit.)

viscosity

1,275-3,500 cP, 1 wt. % in H2O(25 °C, Brookfield, spindle #3) (30 rpm)(lit.)

viscosity

-

form

powder

form

powder

form

powder

form

-

density

0.5 g/mL at 25 °C (lit.)

density

0.5 g/mL at 25 °C (lit.)

density

0.5 g/mL at 25 °C (lit.)

density

0.5 g/mL at 25 °C (lit.)

impurities

<5 wt. %

impurities

<5 wt. %

impurities

<5 wt. %

impurities

-

pH

5.0-8.5

pH

5.0-8.5

pH

5.0-8.5

pH

-

particle size

20 mesh (99% through)

particle size

20 mesh (99% through)

particle size

20 mesh (99% through)

particle size

-

Still not finding the right product?

Explore all of our products under Hydroxypropyl cellulose

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000542515
0000542515
0000494678
0000494678
0000491819

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jeremiah F Kelleher et al.
AAPS PharmSciTech, 21(1), 23-23 (2019-12-14)
The development of oral solid dosage forms, such as tablets that contain a high dose of drug(s), requires polymers and other additives to be incorporated at low levels as possible, to keep the final tablet weight low, and, correspondingly, the
Xiaole Qi et al.
International journal of pharmaceutics, 489(1-2), 210-217 (2015-05-10)
To prolong the residence time of dosage forms within gastrointestinal trace until all drug released at desired rate was one of the real challenges for oral controlled-release drug delivery system. Herein, we developed a fine floating tablet via compression coating
Homendra Naorem et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 101, 67-73 (2012-10-27)
The formation constant of triiodide ions from iodine-iodide equilibrium in aqueous-organic solvent or polymer mixed media have been determined spectrophotometrically at three different temperatures 20, 30 and 40°C. The organic solvents chosen for the study are ethylene glycol, 2-methoxy ethanol
View All Related Papers

Global Trade Item Number

SKUGTIN
69806-1G04061826067253
69806-5G04061832896601
191884-250G04061838760333
191884-100G04061835561599
191884-5G04061838760340

Questions

1–4 of 4 Questions  

  1. Is this food grade?

    1 answer

    1. This is not a food grade Hydroxypropyl cellulose. Unless otherwise stated, this product is intended for research use only. It is not suitable for any other purpose, which includes, but is not limited to, unauthorized commercial use, in vitro diagnostic use, or therapeutic use in humans or animals.

      Currently, a food grade Hydroxypropyl cellulose product is not currently offered.

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. In the structure you have mention R group as H or Ethanol. I am using this material for my research purpose and i want to use the structure of this material in MD simulation so could help me out with the exact monomeric unit of the same.

    1 answer

    1. The R group is either 'H' or a chain of 'C3H6O' units. Many groups of each type are present, but the degree of substitution is not determined. The molecular weight is approximately 100,000 g/mol.

      Helpful?

  4. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

Reviews

No rating value

Active Filters