193291

2-Chloropyrimidine

95%

• Empirical Formula (Hill Notation): C₄H₃ClN₂
• CAS Number: 1722-12-9
• Molecular Weight: 114.53
• Beilstein: 107171
• EC Number: 217-020-2
• MDL number: MFCD00006060
• PubChem Substance ID: 24851590
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: 95%
• form: crystals
• bp: 75-76 °C/10 mmHg (lit.)
• mp: 63-66 °C (lit.)
• SMILES string: Clc1ncccn1
• InChI: 1S/C4H3ClN2/c5-4-6-2-1-3-7-4/h1-3H
• InChI key: UNCQVRBWJWWJBF-UHFFFAOYSA-N

Description

General description

2-Chloropyrimidine undergoes cobalt-catalyzed cross-coupling reaction with aryl halides[1].

Application

2-Chloropyrimidine was used in the synthesis of:

• novel bis(2-(pyrimidin-2-yl)ethoxy)alkanes[2]
• 4′-(1,1′-(5-(2-methoxyphenoxy)-[2,2′-bipyrimidine]-4,6-diyl)bis(1H-pyrazol-3,1-diyl)) dianiline fluorescent dye, biosensor for protein assay[3]
• cis- and trans-octahydropyrrolo[2,3]pyridine derivatives[4]
• 2-amino-4-heteroarylpyrimidines[5]

Packaging

10, 50 g in glass bottle

Other Notes

Remainder 2-hydroxypyrimidine

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 - H319
• Precautionary Statements: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): 208.4 °F - closed cup
• Flash Point(C): 98 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves