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194484

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride

≥98%

Synonym(s):

PFBHA·HCl

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250 mg

Available to ship TODAYfromMILWAUKEE

$65.70
1 g

Available to ship TODAYfromMILWAUKEE

$174.00

About This Item

Linear Formula:
C6F5CH2ONH2·HCl
CAS Number:
Molecular Weight:
249.57
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
261-057-7
Beilstein/REAXYS Number:
4031190
MDL number:
Assay:
≥98%
Form:
solid

$65.70


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Quality Level

assay

≥98%

form

solid

mp

227 °C (subl.) (lit.)

solubility

water: soluble 50 mg/mL, clear to slightly hazy, colorless

functional group

fluoro

SMILES string

Cl.NOCc1c(F)c(F)c(F)c(F)c1F

InChI

1S/C7H4F5NO.ClH/c8-3-2(1-14-13)4(9)6(11)7(12)5(3)10;/h1,13H2;1H

InChI key

HVMVKNXIMUCYJA-UHFFFAOYSA-N

Application

O-(2,3,4,5,6-Pentafluorobenzyl)hydroxylamine hydrochloride is used:
  • In the preparation of oximes of steroids-bearing keto group.[1]
  • As a derivatization reagent in the determination of thromboxane B2, prostaglandins, amygdalin, and a variety of aldehydes, ketones, and acids.[2]
It is a versatile reagent used for the detection of carbonyl-containing compounds by GC, GC-MS, and other methods.[2]

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1 of 1

This Item
76735219908284769
assay

≥98%

assay

≥99.0% (AT)

assay

98%

assay

98%

solubility

water: soluble 50 mg/mL, clear to slightly hazy, colorless

solubility

H2O: 5%, clear

solubility

water: soluble 50 mg/mL, clear to slightly hazy, colorless to yellow

solubility

water: soluble 50 mg/mL, clear to slightly hazy, colorless to light yellow

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

form

solid

form

solid

form

solid

form

-

mp

227 °C (subl.) (lit.)

mp

212-218 °C, 227 °C (subl.) (lit.)

mp

108-111 °C (lit.)

mp

197-199 °C (lit.)

functional group

fluoro

functional group

-

functional group

hydroxyl

functional group

amide


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Vicente Ferreira et al.
Journal of chromatography. A, 1122(1-2), 255-265 (2006-05-20)
This work presents a thorough study of some aspects critical to the quantitative performance of methods for the determination of volatile aldehydes previously derivatized to pentafluorobenzyl hydroxylamine oximes. The conclusions of the study are further applied to the validation of
Raya Ahmed et al.
Cell reports, 33(11), 108501-108501 (2020-12-17)
A central paradigm in the field of lymphocyte biology asserts that replicatively senescent memory T cells express the carbohydrate epitope CD57. These cells nonetheless accumulate with age and expand numerically in response to persistent antigenic stimulation. Here, we use in vivo deuterium
Petr Vesely et al.
Journal of agricultural and food chemistry, 51(24), 6941-6944 (2003-11-13)
A new, fast, sensitive, and solventless extraction technique was developed in order to analyze beer carbonyl compounds. The method was based on solid-phase microextraction with on-fiber derivatization. A derivatization agent, O-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine (PFBOA), was absorbed onto a divinyl benzene/poly(dimethylsiloxane) 65-microm fiber



Global Trade Item Number

SKUGTIN
194484-1G04061835158164
194484-250MG04061832098661

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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