195421

10,11-Dihydrocarbamazepine

99%

• Synonym(s): 10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide
• Empirical Formula (Hill Notation): C₁₅H₁₄N₂O
• CAS Number: 3564-73-6
• Molecular Weight: 238.28
• NACRES: NA.22
• PubChem Substance ID: 24851693
• UNSPSC Code: 12352100
• EC Number: 222-649-0
• MDL number: MFCD00005072
• Assay: 99%
• Form: solid

Properties

• Quality Segment: 100
• assay: 99%
• form: solid
• mp: 205-210 °C (lit.)
• solubility: dichloromethane: soluble 2.5%, clear, colorless
• functional group: amine
• SMILES string: NC(=O)N1c2ccccc2CCc3ccccc13
• InChI: 1S/C15H14N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-8H,9-10H2,(H2,16,18)
• InChI key: PHNLCHMJDSSPDQ-UHFFFAOYSA-N

Description

General description

10,11-Dihydrocarbamazepine is an impurity present in dibenzazepine drug used in the treatment of epilepsy. Single-crystal structure of new dimer-based polymorph of 10,11-dihydrocarbamazepine has been investigated.

Application

10,11-Dihydrocarbamazepine was used as internal standard during simultaneous determination of carbamazepine and its active metabolite in plasma by liquid chromatography[1]. It was used in chemiluminescence method for determination of carbamazepine[2].

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H317,H336,H360D
• pcodes: P201 - P280 - P301 + P312 + P330 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1A - Skin Sens. 1A - STOT SE 3
• target_organs: Central nervous system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable