196665

3-Fluoropyridine

99%

• Synonym(s): 3-Fluoropyridine
• Linear Formula: FC₅H₄N
• CAS Number: 372-47-4
• Molecular Weight: 97.09
• Beilstein/REAXYS Number: 1363666
• EC Number: 206-755-4
• MDL number: MFCD00006374
• UNSPSC Code: 12352100
• PubChem Substance ID: 24851781
• NACRES: NA.22

Properties

• assay: 99%
• form: liquid
• refractive index: n20/D 1.472 (lit.)
• bp: 107-108 °C (lit.)
• density: 1.13 g/mL at 25 °C (lit.)
• functional group: fluoro
• SMILES string: Fc1cccnc1
• InChI: 1S/C5H4FN/c6-5-2-1-3-7-4-5/h1-4H
• InChI key: CELKOWQJPVJKIL-UHFFFAOYSA-N

Description

General description

3-Fluoropyridine is oxidized to corresponding N-oxides, which on treatment with hot acetic anhydride and hydrolysis yields 3-halo-2-pyridones[1]. Microwave spectrum of 3-fluoropyridine has been investigated in the frequency range of 8-18GHz at dry ice temperature[2]. Deprotonation of 3-fluoropyridine with Bu₃MgLi in THF at -10°C has been studied[3].

Application

3-Fluoropyridine was used in the synthesis of 3-halopyridin-4-yl-boronic acids and esters[4].

Safety Information

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H315,H319,H335
• pcodes: P210 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 55.4 °F - closed cup
• flash_point_c: 13 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter