198048

Trimethylaluminum solution

2.0 M in toluene

• Synonym(s): Trimethylalane
• Linear Formula: (CH₃)₃Al
• CAS Number: 75-24-1
• Molecular Weight: 72.09
• Beilstein: 3587197
• MDL number: MFCD00008252
• PubChem Substance ID: 24851857
• NACRES: NA.22

Properties

• form: liquid
• Quality Level: 200
• concentration: 2.0 M in toluene
• density: 0.81 g/mL at 25 °C
• SMILES string: C[Al](C)C
• InChI: 1S/3CH3.Al/h3*1H3;
• InChI key: JLTRXTDYQLMHGR-UHFFFAOYSA-N

Description

Application

Trimethylaluminum solution can be used as a reagent in the synthesis of:

• Polyhydroxylated cyclohexanes by stereoselective rearrangement of unsaturated glycosides.
• Partially hydrolyzed trimethylaluminum (PHT) catalyst for the polymerization of olefins.
• Methyl benzene by methylation of anisole derivatives using nickel-1,3-dicyclohexylimidazol-2-ylidene catalyst system.

Used in a recently reported Al-catalyzed oxidation based on Oppenauer chemistry providing excellent yields of aldehydes and ketones. As a (1:1) complex with binol catalyzes the dynamic kinetic resolution of secondary alcohols with Novozym 435.

Packaging

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

View returnable container options.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS02,GHS05,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H250 - H260 - H304 - H314 - H336 - H361d - H373 - H412
• Precautionary Statements: P210 - P231 + P232 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 3 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 2 - STOT SE 3 - Water-react 1
• Target Organs: Central nervous system
• Supplementary Hazards: EUH014
• Storage Class Code: 4.2 - Pyrophoric and self-heating hazardous materials
• WGK: WGK 3
• Flash Point(F): 39.2 °F - closed cup
• Flash Point(C): 4 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves