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3-Methyl-2-oxopentanoic acid sodium salt


Ketoisoleucine sodium salt, 2-Keto-3-methylvaleric acid sodium salt, 3-Methyl-2-oxopentanoic acid sodium salt
Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level




204-206 °C (lit.)

SMILES string




InChI key


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3-Methyl-2-oxopentanoic acid sodium salt may be used in chemical synthesis studies.


5 g in glass bottle

Storage Class Code

11 - Combustible Solids

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Analysis of (S)- and (R)-3-methyl-2-oxopentanoate enantiomorphs in body fluids.
P Schadewaldt
Methods in enzymology, 324, 33-39 (2000-09-16)
Hsueh-Meei Huang et al.
Biochimica et biophysica acta, 1637(1), 119-126 (2003-01-16)
Mitochondrial dysfunction occurs in many neurodegenerative diseases. The alpha-ketoglutarate dehydrogenase complex (KGDHC) catalyzes a key and arguably rate-limiting step of the tricarboxylic acid cycle (TCA). A reduction in the activity of the KGDHC occurs in brains and cells of patients...
N H McClenaghan et al.
Pancreas, 20(1), 38-46 (2000-01-12)
Insulin-releasing effects of 2-ketobutyric acid (KB), 2-ketoisocaproic acid (KIC), 2-keto-3-methylvaleric acid (KMV), and 3-phenylpyruvic acid (PP) were examined by using clonal beta cells. Whereas KIC, KMV, and PP dose-dependently initiated insulin secretion and potentiated the effects of 4.2-16.7 mM glucose...
M Reis et al.
Biochimica et biophysica acta, 1475(2), 114-118 (2000-06-01)
Maple syrup urine disease is a metabolic disorder caused by mutations of the branched chain keto acid dehydrogenase complex, leading to accumulation of alpha-keto acids and their amino acid precursors in the brain. We now report that alpha-ketoisovaleric, alpha-keto-beta-methyl-n-valeric and...
Michele Sugantino et al.
Biochemistry, 42(1), 191-199 (2003-01-08)
The panB gene that encodes ketopantoate hydroxymethyltransferase has been cloned from Mycobacterium tuberculosis, expressed, and purified to homogeneity. 1H NMR spectroscopy was used to determine the rate of (i) tetrahydrofolate-independent hydroxymethyltransferase chemistry between formaldehyde and alpha-ketoisovalerate and (ii) deuterium exchange...

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