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MilliporeSigma

199311

Tetrabromophenol Blue

Dye content 75 %

Synonym(s):

3,3′,3″,4,5,5′,5″,6-Octabromophenolsulfonphthalein

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About This Item

Empirical Formula (Hill Notation):
C19H6Br8O5S
CAS Number:
4430-25-5
Molecular Weight:
985.54
Beilstein/REAXYS Number:
378438
EC Number:
224-622-9
MDL number:
MFCD00005876
UNSPSC Code:
12171500
PubChem Substance ID:
24851906
NACRES:
NA.47

Key Documents

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assay

≥75.0% (HPLC)

Quality Level

200

form

powder

composition

Dye content, 75%

technique(s)

microbe id | staining: suitable

mp

204 °C (dec.) (lit.)

λmax

388 nm (2nd)
605 nm

ε (extinction coefficient)

≥55000 at 606-616 nm in ethanol and water

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

Oc1c(Br)cc(cc1Br)C2(OS(=O)(=O)c3c(Br)c(Br)c(Br)c(Br)c23)c4cc(Br)c(O)c(Br)c4

InChI

1S/C19H6Br8O5S/c20-7-1-5(2-8(21)16(7)28)19(6-3-9(22)17(29)10(23)4-6)11-12(24)13(25)14(26)15(27)18(11)33(30,31)32-19/h1-4,28-29H

InChI key

QPMIVFWZGPTDPN-UHFFFAOYSA-N

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1 of 4

This Item
236047510998114405
Tetrabromophenol Blue Dye content 75 %

Sigma-Aldrich

199311

Tetrabromophenol Blue

Tetrabromophenol Blue sodium salt Dye content 85 %, ≥84.5% (HPLC)

Sigma-Aldrich

236047

Tetrabromophenol Blue sodium salt

Bromochlorophenol Blue Dye content 95 %

Sigma-Aldrich

510998

Bromochlorophenol Blue

Bromophenol Blue sodium salt Dye content 90 %, ACS reagent

Sigma-Aldrich

114405

Bromophenol Blue sodium salt

technique(s)

microbe id | staining: suitable

technique(s)

titration: suitable

technique(s)

-

technique(s)

titration: suitable

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

form

powder

form

powder

form

powder

form

powder

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

composition

Dye content, 75%

composition

Dye content, 85%

composition

Dye content, 95%

composition

Dye content, 90%

assay

≥75.0% (HPLC)

assay

≥84.5% (HPLC)

assay

-

assay

-

Biochem/physiol Actions

Tetrabromophenol Blue (TBPB) belongs to the group of sulfonephthalein acid-base indicators. It is employed in the potentiometric titration of the halogens with Hg2(NO3)2.[1] In addition, it has been used as a dye indicator in urine dipstick test to detect proteinuria. In this assay, with increasing concentration of urinary protein, TBPB sequentially changes color from pale green to blue. Binding of TBPB to proteins is dependent on pH.[2]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN1323
BCCK5767
BCCH5647
BCCJ7165
BCCD3423

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David S. Breslow, Herman Skolnik
Multi-Sulfur and Sulfur and Oxygen Five- and Six-Membered Heterocycles, Part 1 (2009)
Urine proteomics: the present and future of measuring urinary protein components in disease.
Barratt J and Topham P
CMAJ : Canadian Medical Association Journal = Journal de l'Association Medicale Canadienne, 177, 361-368 (2007)
Liping Li et al.
Analytica chimica acta, 1062, 102-109 (2019-04-06)
The facile detection of phosphopeptides is important for clinical screening and phosphoproteomic research. This work develops an instrument-free, cost-effective, convenient paper-based method for quantitative analysis of phosphorylated peptides. With a novel portable device, Phos-PAD, this method can achieve selective enrichment
Weirui Tan et al.
ACS applied materials & interfaces, 9(48), 42366-42371 (2017-11-09)
Chemical-responsive adhesive sensing chip is a new low-cost analytical platform that uses adhesive tape loaded with indicator reagents to detect or quantify the target analytes by directly sticking the tape to the samples of interest. The chemical-responsive adhesive sensing chips
Andrea Pastore et al.
Sensors (Basel, Switzerland), 20(21) (2020-10-30)
A pH colorimetric sensor array was prepared and characterized by combining tetrabromophenol blue (TBB) and bromothymol blue (BB) embedded in organically modified silicate (OrMoSil) spots polyvinylidene fluoride (PVDF)-supported. The signal was based on the Hue profile (H). The individual calibrations
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