210153

Sigma-Aldrich

2,2,5-Trimethyl-1,3-dioxane-4,6-dione

97%

Synonym(s):
Methyl Meldrum’s acid, cycl-Isopropylidene methylmalonate, Methylmalonic acid cyclic isopropylidene ester
Empirical Formula (Hill Notation):
C7H10O4
CAS Number:
Molecular Weight:
158.15
Beilstein/REAXYS Number:
124044
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

assay

97%

mp

111-114 °C (lit.)

SMILES string

CC1C(=O)OC(C)(C)OC1=O

InChI

1S/C7H10O4/c1-4-5(8)10-7(2,3)11-6(4)9/h4H,1-3H3

InChI key

KJMCAXYHYPDRAV-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

X-ray irradiated single crystals of 2,2,5-trimethyl-1,3-dioxane-4,6-dione have been investigated by electron spin resonance (ESR), electron nuclear double resonance (ENDOR) and electron-electron double resonance (ELDOR) spectra.

Application

2,2,5-Trimethyl-1,3-dioxane-4,6-dione was used for trapping the adduct formed during the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates.

Packaging

25 g in glass bottle

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

An ESR, ENDOR, and ELDOR study of tunneling rotation of a hindered methyl group in x-irradiated 2, 2, 5-trimethyl-1, 3-dioxane-4, 6-dione crystals.
Geoffroy M, et al.
J. Chem. Phys. , 70(9), 4238-4242 (2008)
Issa Yavari et al.
Molecular diversity, 10(2), 247-250 (2006-06-14)
The adduct produced in the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates was trapped by 2,2,5-trimethyl-1,3-dioxane-4,6-dione (methyl Meldrum's acid), to afford highly functionalized ketenimines in good yields.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service

Social Media

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon

MilliporeSigma

Research. Development. Production.

We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

© 2021 Merck KGaA, Darmstadt, Germany and/or its affiliates. All Rights Reserved.

Reproduction of any materials from the site is strictly forbidden without permission.