3-(Dimethylamino)-1,2-propanediol

Name: 3-(Dimethylamino)-1,2-propanediol
Brand: ALDRICH
Price: 130 USD

98%

Synonym(s):

(±)-3-(Dimethylamino)-1,2-propanediol, 1,2-Dihydroxy-3-(dimethylamino)propane, Methicol

Slide 1 of 1

Select a Size

25 ML

$130.00

Check Cart for Availability

Request a Bulk Order

About This Item

Linear Formula:

(CH₃)₂NCH₂CH(OH)CH₂OH

CAS Number:

623-57-4

Molecular Weight:

119.16

NACRES:

NA.22

PubChem Substance ID:

24852622

UNSPSC Code:

12352100

EC Number:

210-802-4

MDL number:

MFCD00004714

Assay:

98%

Key Documents

View All Documentation

InChI key

QCMHUGYTOGXZIW-UHFFFAOYSA-N

InChI

1S/C5H13NO2/c1-6(2)3-5(8)4-7/h5,7-8H,3-4H2,1-2H3

SMILES string

CN(C)CC(O)CO

assay

98%

refractive index

n20/D 1.4609 (lit.)

bp

216-217 °C (lit.)

density

1.004 g/mL at 25 °C (lit.)

functional group

amine, hydroxyl

Quality Level

200

Related Categories

Organic Building Blocks

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item	559296	278440	M75209
Sigma-Aldrich 210218 3-(Dimethylamino)-1,2-propanediol	Sigma-Aldrich 559296 2-Phenyl-1,3-propanediol	Sigma-Aldrich 278440 2-{[2-(Dimethylamino)ethyl]methylamino}ethanol	Sigma-Aldrich M75209 2-Methyl-2-propyl-1,3-propanediol
assay 98%	assay 98%	assay 98%	assay 98%
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 100
refractive index n20/D 1.4609 (lit.)	refractive index -	refractive index n20/D 1.4539 (lit.)	refractive index -
bp 216-217 °C (lit.)	bp -	bp 207 °C (lit.)	bp 230 °C/753 mmHg (lit.)
density 1.004 g/mL at 25 °C (lit.)	density -	density 0.904 g/mL at 25 °C (lit.)	density -
functional group amine	functional group hydroxyl, phenyl	functional group amine, hydroxyl	functional group -

Application

3-(Dimethylamino)-1,2-propanediol was used in the preparation of:

synthetic cationic lipid, N-[1-(2,3-dioleyloxy)propyl-N,N,N-trimethylammonium chloride (DOTMA), used in DNA-transfection protocol[1]
indane-derived bis(oxazolines)[2]

pictograms

GHS05

signalword

Danger

hcodes

H314

pcodes

P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

221.0 °F - closed cup

flash_point_c

105 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

An efficient synthesis of indane-derived bis (oxazoline) and its application to hetero Diels-Alder reactions on polymer support.

Kurosu M, et al.

Tetrahedron Letters, 45(1), 145-148 (2004)

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

P L Felgner et al.

Proceedings of the National Academy of Sciences of the United States of America, 84(21), 7413-7417 (1987-11-01)

A DNA-transfection protocol has been developed that makes use of a synthetic cationic lipid, N-[1-(2,3-dioleyloxy)propyl]-N,N,N-trimethylammonium chloride (DOTMA). Small unilamellar liposomes containing DOTMA interact spontaneously with DNA to form lipid-DNA complexes with 100% entrapment of the DNA, DOTMA facilitates fusion of

Liposome-like nanocapsules of dual drug-tailed betaine for cancer therapy.

Shuo Fang et al.

International journal of pharmaceutics, 493(1-2), 460-465 (2015-08-11)

A novel dual drug-tailed betaine conjugate amphiphile has been firstly synthesized in which the polar headgroup is derived from glycine betaine and the hydrophobic tails are chlorambucil molecules. The newly prepared conjugate undergoes self-assembly to form stable liposome-like nanocapsules as

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service